Results 31 to 40 of about 58,693 (288)

Effects of Fermented Kefir as a Functional Feed Additive in Litopenaeus vannamei Farming

open access: yesFermentation, 2020
Litopenaeus vannamei, known as whiteleg shrimp, is susceptible to infection by pathogenic microorganisms such as viruses and bacteria. Therefore, the prevention of infections in this shrimp is important to regulate the outbreaks of pathogenic ...
Woosik Choi   +6 more
doaj   +1 more source

Comparison of bioactive compounds and health promoting properties of fruits and leaves of apple, pear and quince

open access: yesScientific Reports, 2021
This paper presents characterization of healthy potential new sources of functional constituents with reference to basic plant sources. In this study, the phenolics, triterpene, isoprenoids (chlorophylls and carotenoids), amino acids, minerals, sugars ...
Aneta Wojdyło   +4 more
doaj   +1 more source

6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Aiming to deepen the structure–activity relationships of the two P-glycoprotein (P-gp) modulators elacridar and tariquidar, a new series of amide and ester derivatives carrying a 6,7-dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline scaffold linked to
Laura Braconi   +11 more
doaj   +1 more source

Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors

open access: yesFrontiers in Chemistry, 2020
Human neutrophil elastase (HNE) is involved in a number of essential physiological processes and has been identified as a potential therapeutic target for treating acute and chronic lung injury.
Letizia Crocetti   +7 more
doaj   +1 more source

Repurposing strategies on pyridazinone-based series by pharmacophore- and structure-driven screening

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
We report here in silico repurposing studies on 52 new pyridazinone-based small-molecules through inverse virtual screening (iVS) methodologies. These analogues were originally designed as formyl peptide receptor (FPR) ligands.
Giuseppe Floresta   +4 more
doaj   +1 more source

A comparative study of calcium absorption following a single serving administration of calcium carbonate powder versus calcium citrate tablets in healthy premenopausal women

open access: yesFood & Nutrition Research, 2014
Background: Calcium is an essential mineral often taken as a daily, long-term nutritional supplement. Data suggests that once-daily dosing is important with regard to long-term compliance of both drugs and nutritional supplements.
Haiyuan Wang   +2 more
doaj   +1 more source

Kerala's ICAR Institute Claims to have developed Nutraceutical to Boost Post-Covid Immunity BQ Prime dated 24th July 2023 [PDF]

open access: yes, 2023
The Central Marine Research Institute has developed a nutraceutical product from select seaweeds that boosts innate immunity against post-Covid complications.
CMFRI, Library
core   +1 more source

Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
Click chemistry reactions constitute an important and relatively new approach in the medicinal chemistry toolbox and offer substantial advantages to medicinal chemists in terms of overcoming the limitations of facile chemical synthesis, increased ...
Andrea Angeli, Claudiu T. Supuran
doaj   +1 more source

Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2022
Coumarins were discovered to act as inhibitors of α-carbonic anhydrases (CAs, EC 4.2.1.1) after undergoing hydrolysis mediated by the esterase activity of the enzyme to the corresponding 2-hydroxycinnamic acids.
Simone Giovannuzzi   +4 more
doaj   +1 more source

Antithrombotic Effect of the Ethanol Extract of Angelica gigas Nakai (AGE 232)

open access: yesLife, 2021
Cardiovascular diseases, such as stroke, are the most common causes of death in developed countries. Ischemic stroke accounts for 85% of the total cases and is caused by abnormal thrombus formation in the vessels, causing deficient blood and oxygen ...
Pia Loreto Werlinger Bravo   +6 more
doaj   +1 more source

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