Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Clostridioides difficile minimal nutrient requirements for flagellar motility. [PDF]
Front Microbiol, 2023 Schwanbeck J +3 more
europepmc +1 more source
The effect of food provisioning on the nutrient intake of wild and captive primates : implications for the conservation management of wild and captive populations : a thesis presented in partial fulfilment of the requirements for the degree of Doctorate of Philosophy in Ecology, Massey University, Albany, New Zealand [PDF]
, 2017 Many non-human primate populations worldwide are threatened with extinction. Various measures are taken to save these species. Amongst these efforts are habitat protection, restoration, and public education, including wildlife tourism.
Kreigenhofer, Brigitte Monique
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Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Media Peternakan, 2008 The aim of this study was to obtain information in relation to kind of forest plants which were usually consumed by mountain anoa in its natural habitat and community area around the forest, and to estimate energy and nutrient requirements for ...
M. Basri +3 more
doaj
Perspective: Is It Time to Revise the Current Nutrient Requirements for Infant Formulas Principally Established in 1980? [PDF]
Adv Nutr, 2023 Abrams SA, Bergner EM.
europepmc +1 more source
How Baywide Nutrient Trading Could Benefit Maryland Farms [PDF]
, 2010 Outlines pending legislation to improve the health of the Chesapeake Bay watershed, including a nutrient trading program that allows farms that reduce runoff of nutrients to below target to sell "credits." Estimates costs, credits, and credit ...
Cy Jones +4 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Liver-based infant complementary food [PDF]
, 2018 - Weaning of infants involves the gradual introduction of solid foods and fluids along with the usual milk fed in their diet. After around six month of age, it becomes difficult to meet the nutritional requirements from the breast milk alone.
Farouk, M.M. +2 more
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