Results 111 to 120 of about 520,936 (312)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Chemical studies of nutrient requirements of corn and milo [PDF]

open access: yes, 1953
Call number: LD2668 .T4 1953 K6Master of ...
Knauss, Carl Jacob.
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Protein requirement for Trichogaster lalius, blue variety

open access: yesRevista Brasileira de Zootecnia, 2013
The objective of the present study was to evaluate the protein requirement of juvenile Trichogaster lalius, blue variety. The experimental design was of randomised blocks (B1 = initial weight of 1.04±0.05 g and B2 = 1.36±0.02 g), with two replicates ...
Jener Alexandre Sampaio Zuanon   +6 more
doaj  

Nutrient Utilization and Requirements in Sheep and Goats Raised Under Different Systems and Fed Low Nutritional Novel Feeds for Meat Production

open access: yesAnimals
Sheep and goats are essential in many parts of the world, providing meat, milk, and fiber while also aiding rural and low-income communities. The cost of feeding is a major factor in the overall expenses of animal production.
Osman Mahgoub   +2 more
doaj   +1 more source

NY Pollution Discharge Elimination Permits for CAFOs, Management Adjustments and the Environment [PDF]

open access: yes
Weakening demand for livestock and dairy produce, historically high prices for feed ingredients and increasingly strict regulations on animal waste management continue to put significant pressure on livestock and dairy operating margins.
Boisvert, Richard N.   +2 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Circular 68 [PDF]

open access: yes, 1989
Livestock rations should be balanced for many parameters including protein, and various minerals, and energy, to ensure that all required nutrients are present in the adequate amounts and proper relationships. Energy content is the primary consideration
Bruce, Leroy Ben, Herlugson, Mary Lou
core  

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