Results 81 to 90 of about 520,936 (312)

Controlled ecological life support systems: Development of a plant growth module [PDF]

open access: yes
An effort was made to begin defining the scientific and technical requirements for the design and construction of a ground-based plant growth facility. In particular, science design criteria for the Plant Growth Module (PGM) of the Controlled Ecological ...
Averner, Mel M.   +2 more
core   +1 more source

Assessing nutrient and sediment transport for Water Framework Directive purposes using the SWAT model - a case study in SW Finland [PDF]

open access: yes, 2006
The ecological status of lake Pyhäjärvi, located in south-western Finland, may be classified as moderate due to its elevated nutrient concentrations and algal biomass production.
Bärlund, Ilona   +2 more
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Characterisation of dairy soiled water in a survey of 60 Irish dairy farms [PDF]

open access: yes, 2016
peer-reviewedDairy farming in Ireland generates an effluent known as dairy soiled water (DSW), which consists of a relatively dilute mixture of cow faeces, urine, spilt milk and detergents that is typically applied to grassland.
Bolger, Thomas   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Challenges in organic egg-production related to the nutritional quality of foraging material and introduction of 100% organic feeding [PDF]

open access: yes, 2009
Organc hens have daily access to foraging material and the quality are important for egg-production due to varying contents of amino acids (aa) and dietary fibres (Hammershøj and Steenfeldt, 2005; Steenfeldt et al., 2007).
Hammershøj, M., Steenfeldt, S.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Risk management on application of minimum-cost feed ration for nitrogen and phosphorus reduction on dairy farm [PDF]

open access: yes
The traditional mathematical programming model with the objective function of feed ration cost minimization is used to accommodate risk management responses to price variability associated with feeding a particular feed ration over time.
Dillon, Carl R.   +2 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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