Results 31 to 40 of about 42,562 (259)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Traffic light nutrition labeling preferences among children

Agricultural and Food Economics, 2023
Objective This study evaluates the effects of traffic light (TL) nutritional label attributes on children’s food choices. Data were collected from a survey of 1179 Ecuadorian students attending public middle and high school in three major cities in the ...
Tania Cabrera, Carlos E. Carpio, Oscar Sarasty, Susan E. Watson, María-Susana Gonzalez   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Perception of the use and understanding of nutrition labels among different socioeconomic groups in Mexico: a qualitative study

Salud Pública de México, 2020
Objective. To explore the perception of the use and comprehension of the nutrition labeling (GDA, NFT, NS) and claims in packaged foods among different socio economic-status (SES). Materials and methods. This was a qualitative study, 12 focus groups were
Claudia Nieto, Jacqueline Alcalde-Rabanal, Carmen Mena, Ángela Carriedo, Simón Barquera   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison and implications of nutrition labels in China and Republic of Korea

Zhongguo shipin weisheng zazhi
With the improvement of living standards and the increasing burden of chronic diseases， nutrition labeling plays an increasingly important role in safeguarding consumer’s right to know， guiding healthy dietary choices， and regulating the food industry ...
PAN Fang, LIU Li, HUANG Xiongjun, ZHANG Haiyan, LIAO Rongjun, LIN Meifang, LIU Jianjia, YI Rong   +7 more
doaj   +1 more source

Determinants of Israeli consumers’ decision to use food label information more frequently: a national survey study

Israel Journal of Health Policy Research, 2021
Background Food labeling to encourage healthier food choices may have positive long-term effects. Yet previous studies point to challenges in terms of how consumers understand and use labeling information.
Shosh Shahrabani
doaj   +1 more source