Results 141 to 150 of about 18,666 (287)

Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu   +7 more
wiley   +1 more source

Information Transmission Strategies for Self‐Organized Robotic Aggregation

open access: yesAdvanced Robotics Research, EarlyView.
In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng   +5 more
wiley   +1 more source

Physical activity calorie equivalent (PACE) food labelling on discretionary foods in secondary school canteens in England: an efficacy cluster randomised controlled trial

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity
Background Schools do not typically implement food labelling in their canteens, therefore young people may not be given nutrition information on which to make their food choices.
Natalia Iris   +2 more
doaj   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang   +13 more
wiley   +1 more source

Indirect Effects of Eco-labelling of agricultural products on Natural Resources

open access: yes
The implementation of eco-labelling schemes for agricultural and food products may represent an opportunity to enhance production technologies compatible with the sustainable economic approach.
Viscecchia, Rosaria, Prosperi, Maurizio
core  

Disruption of millipede-gut microbiota in E. pulchripes and G. connexa highlights the limited role of litter fermentation and the importance of litter-associated microbes for nutrition

open access: yesCommunications Biology
Millipedes are thought to depend on their gut microbiome for processing plant-litter-cellulose through fermentation, similar to many other arthropods. However, this hypothesis lacks sufficient evidence.
Julius Eyiuche Nweze   +5 more
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

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