Results 41 to 50 of about 146,732 (317)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Machine learning-based prediction of vitamin D deficiency: NHANES 2001-2018

Frontiers in Endocrinology
BackgroundVitamin D deficiency is strongly associated with the development of several diseases. In the current context of a global pandemic of vitamin D deficiency, it is critical to identify people at high risk of vitamin D deficiency.
Jiale Guo, Qionghan He, Yehai Li
doaj   +1 more source

Sodium intake according to NOVA food classification in Brazil: trends from 2002 to 2018 [PDF]

Cadernos de Saúde Pública
: Excessive sodium intake is a major global public health issue and the identification of dietary sources and temporal trends in its consumption are a key to effective sodium reduction policies.
Eduardo Augusto Fernandes Nilson, Giovanna Calixto Andrade, Rafael Moreira Claro, Maria Laura da Costa Louzada, Renata Bertazzi Levy   +4 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Dyslipidemia prevalence, awareness, treatment and control in Mexico: results of the Ensanut 2012

Salud Pública de México, 2020
Objective. To describe in a national sample 1) the preva­lence, awareness, treatment and control of dyslipidemias 2) the prevalence of dyslipidemias through previous national surveys. Materials and methods.
César Hernández-Alcaraz, Carlos A Aguilar-Salinas, Kenny Mendoza-Herrera, Andrea Pedroza-Tobías, Salvador Villalpando, Teresa Shamah-Levy, Juan Rivera-Dommarco, Mauricio Hernández-Ávila, Simón Barquera   +8 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Household water security and infant feeding practices in Mexico: insights from the ENSANUT 2021 survey

BMC Public Health
Summary Background Water security (WS) and improved socioeconomic conditions are crucial for child nutrition. However, limited research has explored the association between WS and infant and young child feeding (IYCF) practices in low- and middle-income ...
Gandy Dolores-Maldonado, Verónica Mundo Rosas, Luz Dinorah Gonzalez-Castell, Eric Monterrubio-Flores   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source