WP(Pip) is a mixture of whey protein and piperine‐loaded nanoemulsion stabilized by WP through microfluidic homogenization. Acting as a “smart key,” piperine opens epithelial tight junctions to enhance absorption of whey protein and, thereby increasing circulating amino acid availability, synergistically up‐regulates the mTOR signaling pathway in ...
Qing Yue +10 more
wiley +1 more source
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui +8 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of l-isoleucine produced with <i>Corynebacterium glutamicum</i>CCTCC M 2022764 for all animal species (Innobio Europe B.V.). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +21 more
europepmc +1 more source
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li +8 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of l-lysine sulfate produced using <i>Corynebacterium glutamicum</i>KCCM 80368 for all animal species (CJ Europe GmbH). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +22 more
europepmc +1 more source
Nutritional additives in high moisture corn silage
M. Calixto Junior +3 more
openaire +2 more sources
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng +8 more
wiley +1 more source
Assessment of the feed additive consisting of astaxanthin (2a161j) for fish, crustaceans and ornamental fish for the renewal of its authorisation (BASF SE, DSM Nutritional Products Ltd., JYB Europe BV, NHU EUROPE GmbH). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +27 more
europepmc +1 more source
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen +28 more
wiley +1 more source
Assessment of the feed additive consisting of betaine anhydrous (3a920) for all animal species for the renewal of its authorisation (Genencor International B.V.). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +21 more
europepmc +1 more source

