Results 21 to 30 of about 5,136,783 (298)

Nutrigenomics: A budding cross-over [PDF]

Scripta Medica
Nutrigenomics is a rapidly developing subject that combines genomics and nutrition to reveal the complex interactions between our genetic composition and the foods we consume. This review paper provides a thorough overview of nutrigenomics, exploring its
Aggarwal Navidha, Malik Rohit, Mittal Arun, Tushir Shiva, Chopra Shivani, Chopra Hitesh   +5 more
doaj   +1 more source

TNFα is a key trigger of inflammation in diet-induced non-obese MASLD in mice

Redox Biology, 2023
Tumor necrosis factor alpha (TNFα) is thought to be a critical factor in the development of metabolic dysfunction-associated steatotic liver disease (MASLD).
Katharina Burger, Finn Jung, Anja Baumann, Annette Brandt, Raphaela Staltner, Victor Sánchez, Ina Bergheim   +6 more
doaj   +1 more source

The Role of the Food and Nutritional Sciences in Examining the Determinants of Health

, 2015
Typically the food and nutritional sciences have been reviewed and viewed in isolation in regard to human health. However, the food and nutritional sciences are both dynamic and interactive disciplines that transcend the traditional labels often employed
Melissa Johnson
semanticscholar   +1 more source

The effects of breastfeeding and formula feeding on the metabolic factors and the expression level of obesity and diabetes‐predisposing genes in healthy infants

Physiological Reports, 2022
Diabetes mellitus (DM) and obesity are common illnesses characterized by glucose metabolism issues and excessive weight gain. Breastfeeding is the best way to feed a newborn up to 6 months old and it has been shown to reduce the risk of diabetes and ...
Sahar Cheshmeh, Seyed Mostafa Nachvak, Niloofar Hojati, Negin Elahi, Neda Heidarzadeh‐Esfahani, Amir Saber   +5 more
doaj   +1 more source

Bi-directional ribosome scanning controls the stringency of start codon selection

Nature Communications, 2021
Start codon selection is commonly thought to occur through the unidirectional scanning of the mRNA by the 40 S ribosome. Here the authors provide evidence that the pre-initiation complex can backslide on the mRNA to initiate translation at upstream AUG ...
Yifei Gu, Yuanhui Mao, Longfei Jia, Leiming Dong, Shu-Bing Qian   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Impact of an undergraduate course on medical students’ self-perceived nutrition intake and self-efficacy to improve their health behaviours and counselling practices [PDF]

Journal of Primary Health Care, 2014
INTRODUCTION: Doctors are increasingly involved in the management of chronic disease and counsel patients about their lifestyle behaviours, including nutrition, to improve their health outcomes.
Crowley J, Ball L, Leveritt MD, Arroll B, Han DY, Wall C   +5 more
doaj  

The inhibitory SAPS3–AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice

FEBS Letters, EarlyView.
This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk, Maria A. Møller, Jørgen F.P. Wojtaszewski, Rasmus Kjøbsted   +3 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source