Results 61 to 70 of about 4,022,887 (313)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Understanding the nutritive value of pasture mixtures [PDF]

, 2017
An investigation of how nutritive value changes with respect to the number of species and proportions of species in pasture mixtures was carried out at Lincoln University. Tetraploid perennial ryegrass cv. Base, plantain cv. Tonic, white clover cv.
Vreugdenhil, Sonja Renee
core  

Feed ingredients and nutritive value of the diet.

, 2018
Feed ingredients and nutritive value of the diet.
Piotr Dobrowolski (2333500), Małgorzata Kwiecień (4801440), Tomasz Blicharski (4112560), Anna Milczarek (4036724), Siemowit Muszyński (4112557), Renata Klebaniuk (5029769), Ewa Tomaszewska (4112566), Sylwia Szymańczyk (5029763), Agnieszka Tomczyk-Warunek (4801437), Sylwester Kowalik (5029766)   +9 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

EVALUACIÓN COMPARATIVA DE LOS ATRIBUTOS NUTRICIONALES Y ANTINUTRICIONALES DE LEGUMINOSAS SUBUTILIZADAS, Canavalia gladiata (JACQ.) DC, Erythrina indica LAM. Y Abrus precatorius L

Tropical and Subtropical Agroecosystems, 2012
Se colectaron muestras de semillas de of Canavalia gladiata, Erythrina indica y Abrus precatorius (roja y negra, semilla de cascara colorada y semilla de cascara blanca) de las regiones de Tamil Nadu y se analizó su composición química con la visión ...
Pious Soris Tresina, Veerabahu ramasamy Mohan   +1 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Impact of novel harvest strategies and improved cultivars on alfalfa yield and nutritive value in a Mediterranean environment

Grassland Research
Background The development of alfalfa cultivars with improved digestibility may minimize the yield‐quality tradeoff, enabling higher quality with late‐harvested forage and possibly higher yields.
Sultan Begna, Brenda Perez, Abdelmoneim Z. Mohamed, Katherine Swanson, E. Charles Brummer, Dong Wang, Khaled Bali, Daniel H. Putnam   +7 more
doaj   +1 more source

Nutritive value parameters of seven atriplex spp. around the year

, 1995
Center for Desert Studies, Faculty of Agriculture, King Saud University, Riyadh, Saudi ArabiaAtriplex species could be utilized for range improvement in arid, semiarid and saline lands. These could be browsed nearly the year around.
Al-Sheikh, A.A., El-Din, S.S. Tag
core  

Ontogenesis and nutritive value of warm-season perennial bunch grasses

, 2014
Understanding the dynamics of nutritive values in warm-season perennial bunch grasses with change in ontogenesis is essential to managing their use as forage for livestock or cellulosic bioenergy feedstock.
James P. Muir, Robert D. Ziehr, Joel L. Douglas, Gary L. Rea, George L. Peacock, Kenneth E. Spaeth   +5 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source