Results 31 to 40 of about 183,803 (290)

Identification of Secreted O-Mannosylated Proteins From BCG and Characterization of Immunodominant Antigens BCG_0470 and BCG_0980

Frontiers in Microbiology, 2020
Bacterial glycoproteins have been investigated as vaccine candidates as well as diagnostic biomarkers. However, they are poorly understood in Mycobacterium bovis strain bacille Calmette-Guérin (BCG), a non-pathogenic model of Mycobacterium tuberculosis ...
Guoying Deng, Wenli Zhang, Na Ji, Yunpeng Zhai, Xiaoxia Shi, Xin Liu, Shufeng Yang   +6 more
doaj   +1 more source

Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against Shigella: State-of-the-Art for a Monovalent Prototype and Challenges

Vaccines, 2022
This review focuses on the molecular glycovaccine concept, a promising option to develop a Shigella glycoconjugate vaccine. Subsequent to original developments involving, as main vaccine component, the detoxified Shigella lipopolysaccharide randomly ...
Armelle Phalipon, Laurence A. Mulard
doaj   +1 more source

Mucin-Type O-Glycosylation in Gastric Carcinogenesis

Biomolecules, 2016
Mucin-type O-glycosylation plays a crucial role in several physiological and pathological processes of the gastric tissue. Modifications in enzymes responsible for key glycosylation steps and the consequent abnormal biosynthesis and expression of their ...
Henrique O. Duarte, Daniela Freitas, Catarina Gomes, Joana Gomes, Ana Magalhães, Celso A. Reis   +5 more
doaj   +1 more source

The Antigenic Structure Characterization of Oestrus Ovis Larvae

Scientific Papers Animal Science and Biotechnologies, 2023
With the aim of proteic components definition from Oestrus ovis larvae, endowed with antigenic properties, able to induce immune responses in vivo and to react in vitro with induced molecular effectors were been performed: electrophoresis in ...
Daniela Moţ
doaj  

The value of the Widal test in the diagnosis of Prolonged Septicemic Salmonellosis

Revista do Instituto de Medicina Tropical de São Paulo, 1985
Twenty patients with prolonged septicemic salmonellosis (Group 1) and 20 with schistosomiasis mansoni (Group 2) were selected for this study. In both groups, the Widal test was done using antigens of the sample Ty 901 (S. typhi).
José Roberto Lambertucci, Roberto Pedercini Marinho, Maria das Dores Ferreira, Jayme Neves   +3 more
doaj   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Inter-individual and inter-regional variability of breast milk antibody reactivity to bacterial lipopolysaccharides

Frontiers in Immunology
Breast milk is a vital source of nutrients, prebiotics, probiotics, and protective factors, including antibodies, immune cells and antimicrobial proteins. Using bacterial lipopolysaccharide arrays, we investigated the reactivity and specificity of breast
Lisa Crone, Jens Sobek, Nicole Müller, Tanja Restin, Tanja Restin, Dirk Bassler, Daniela Paganini, Michael B. Zimmermann, Patricia Zarnovican, Françoise H. Routier, Tais Romero-Uruñuela, Luis Izquierdo, Luis Izquierdo, Thierry Hennet   +13 more
doaj   +1 more source

O-Antigen Gene Clusters of Plesiomonas shigelloides Serogroups and Its Application in Development of a Molecular Serotyping Scheme

Frontiers in Microbiology, 2019
Plesiomonas shigelloides is a Gram-negative, flagellated, rod-shaped, ubiquitous, and facultative anaerobic bacterium. It has been isolated from various sources, such as freshwater, surface water, and many wild and domestic animals. P.
Daoyi Xi, Daoyi Xi, Daoyi Xi, Daoyi Xi, Xiaochen Wang, Xiaochen Wang, Xiaochen Wang, Xiaochen Wang, Kexin Ning, Kexin Ning, Kexin Ning, Kexin Ning, Qian Liu, Qian Liu, Qian Liu, Qian Liu, Fuyi Jing, Fuyi Jing, Fuyi Jing, Fuyi Jing, Xi Guo, Xi Guo, Xi Guo, Xi Guo, Boyang Cao, Boyang Cao, Boyang Cao, Boyang Cao   +27 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source