Results 11 to 20 of about 781 (170)

From a toxin to an obesogen: a review of potential obesogenic roles of acrylamide with a mechanistic approach. [PDF]

open access: yesNutrition Reviews, 2023
Abstract Obesity and obesity-related disorders such as cancer, type 2 diabetes, and fatty liver have become a global health problem. It is well known that the primary cause of obesity is positive energy balance. In addition, obesity is the consequence of complex gene and environment interactions that result in excess calorie intake being
Asli Akyol, Yücel Büyükdere
exaly   +5 more sources

Obesogens in Children—An Uncharted Territory [PDF]

open access: yesMetabolites, 2021
Obesogens are exogenous chemicals belonging to the group of endocrine-disrupting chemicals and are believed to interfere in obesity development. In children, several chemicals are under investigation, most commonly bisphenol A, phthalates, perfluorinated
Mirjam Močnik, Nataša Marčun Varda
doaj   +3 more sources

Multi‐miRNAs‐Mediated Hepatic Lepr Axis Suppression: A Pparg–Dicer1 Pathway‐Driven Mechanism in Spermatogenesis for the Intergenerational Transmission of Paternal Metabolic Syndrome

open access: yesAdvanced Science
Bisphenol A (BPA) is an “environmental obesogen” and this study aims to investigate the intergenerational impacts of BPA‐induced metabolic syndrome (MetS), specifically focusing on unraveling mechanisms. Exposure to BPA induces metabolic disorders in the
Yi Lin   +11 more
doaj   +2 more sources

Obesity Induces DNA Damage in Mammary Epithelial Cells Exacerbated by Acrylamide Treatment through CYP2E1-Mediated Oxidative Stress [PDF]

open access: yesToxics
Obesity and environmental toxins are risk factors for breast cancer; however, there is limited knowledge on how these risk factors interact to promote breast cancer.
Brenna Walton   +4 more
doaj   +2 more sources

New Insight Into Male Infertility: Deviation From Basic Tenets of Life. [PDF]

open access: yesOxid Med Cell Longev
Male reproductive health faces mounting concern as global sperm concentration (SC) has declined markedly, with evidence linking this trend to environmental and lifestyle factors rather than natural variability. In parallel, rising rates of obesity, diabetes, and hypertension point to shared mechanisms with infertility, particularly those rooted in diet.
Nasr-Esfahani MH   +3 more
europepmc   +2 more sources

The p-Phthalates Terephthalic Acid and Dimethyl Terephthalate Used in the Manufacture of PET Induce In Vitro Adipocytes Dysfunction by Altering Adipogenesis and Thermogenesis Mechanisms

open access: yesMolecules, 2022
Public health concerns associated with the potential leaching of substances from Polyethylene terephthalate (PET) packaging have been raised due to the role of phthalates as endocrine-disrupting chemicals or obesogens.
Maria Sofia Molonia   +6 more
doaj   +1 more source

Obesogens in Foods

open access: yesBiomolecules, 2022
Obesogens, as environmental endocrine-disrupting chemicals, are supposed to have had an impact on the prevalence of rising obesity around the world over the last forty years. These chemicals are probably able to contribute not only to the development of obesity and metabolic disturbances in individuals, but also in their progeny, having the capability ...
Iva Kladnicka   +4 more
openaire   +5 more sources

Cetyl Alcohol Polyethoxylates Disrupt Metabolic Health in Developmentally Exposed Zebrafish

open access: yesMetabolites, 2023
Alcohol polyethoxylates (AEOs), such as cetyl alcohol ethoxylates (CetAEOs), are high-production-volume surfactants used in laundry detergents, hard-surface cleaners, pesticide formulations, textile production, oils, paints, and other products. AEOs have
Matthew K. LeFauve   +4 more
doaj   +1 more source

Nonylphenol Polyethoxylates Enhance Adipose Deposition in Developmentally Exposed Zebrafish

open access: yesToxics, 2022
Alkylphenol polyethoxylates (APEOs), such as nonylphenol ethoxylates (NPEOs), are high-production-volume surfactants used in laundry detergents, hard-surface cleaners, pesticide formulations, textile production, oils, paints, and other products.
Christopher D. Kassotis   +5 more
doaj   +1 more source

Obesity and endocrine-disrupting chemicals

open access: yesEndocrine Connections, 2021
Obesity is now a worldwide pandemic. The usual explanation given for the prevalence of obesity is that it results from consumption of a calorie dense diet coupled with physical inactivity.
Angelica Amorim Amato   +2 more
doaj   +1 more source

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