The obesogenic side of Genistein [PDF]
Frontiers in Endocrinology, 2023 Genistein (GN) has been highly recommended for its medicinal properties like anticancer, antidiabetic, antihyperlipidemic, antiviral, and antioxidant activities among others. Recently, scientists realized that Genistein is an endocrine disruptor.
Jia Xiang +14 more
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Obesogens in Children—An Uncharted Territory [PDF]
Metabolites, 2021 Obesogens are exogenous chemicals belonging to the group of endocrine-disrupting chemicals and are believed to interfere in obesity development. In children, several chemicals are under investigation, most commonly bisphenol A, phthalates, perfluorinated
Mirjam Močnik, Nataša Marčun Varda
doaj +5 more sources
Obesogenic Dysregulation of Human Periprostatic Adipose Tissue Promotes the Viability of Prostate Cells and Reduces Their Sensitivity to Docetaxel and Cabazitaxel [PDF]
Medical SciencesBackground: Periprostatic adipose tissue (PPAT) has been shown to play a significant role in prostate cancer (PCa) development and progression. This relationship is further exacerbated by obesity, as PPAT-secreted factors increase PCa aggressiveness and ...
Mariana Feijó +9 more
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Current Research Approaches and Challenges in the Obesogen Field [PDF]
Frontiers in Endocrinology, 2019 Obesity is a worldwide pandemic that also contributes to the increased incidence of other diseases such as type 2 diabetes. Increased obesity is generally ascribed to positive energy balance.
Raquel Chamorro-Garcia +3 more
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Transgenerational metabolomic fingerprints in mice ancestrally exposed to the obesogen TBT
Environment International, 2021 Background: Endocrine disrupting chemicals (EDCs) contribute to the etiology of metabolic disorders such as obesity, insulin resistance and hepatic dysfunction. Concern is growing about the consequences of perinatal EDC exposure on disease predisposition
Raquel Chamorro-Garcia +2 more
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Heritable changes in chromatin contacts associated with transgenerational susceptibility to diet-induced insulin dysregulation and obesity [PDF]
Nature CommunicationsEffects of prenatal environmental exposures can be transmitted across generations through the germline without DNA mutations, an example of transgenerational epigenetic inheritance.
Richard C. Chang +14 more
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History of the Obesogen Field: Looking Back to Look Forward
Frontiers in Endocrinology, 2019 The Obesogen field developed from two separate scientific research areas, endocrine disruptors and the Developmental Origins of Health and Disease (DOHaD).
Jerrold J. Heindel
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Endocrine Aspects of Environmental "Obesogen" Pollutants [PDF]
, 2016 Growing evidence suggests the causal link between the endocrine-disrupting chemicals (EDCs) and the global obesity epidemics, in the context in the so-called "obesogenic environment".
Barrea, Luigi +6 more
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The Case for BPA as an Obesogen: Contributors to the Controversy [PDF]
Frontiers in Endocrinology, 2019 Since the inception of the term endocrine disruptor, the idea that the environment is an important determinant of phenotype has motivated researchers to explore the effect of low dose exposure to BPA during organogenesis.
Beverly S. Rubin +2 more
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Dietary Aluminum Exposure Is More Closely Linked to Antioxidant Dynamics than to Body Mass Index [PDF]
ToxicsThe association between aluminum exposure and obesity remains uncertain. This study investigated whether aluminum exposure (dietary, serum, and urinary) is linked to obesity and whether dietary antioxidant capacity moderates this relationship. A total of
Ozge Yesildemir +6 more
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