Results 11 to 20 of about 1,065 (167)

Identification of pharmaceuticals and environmental contaminants as obesogens inducing a locomotion-independent thrifty phenotype [PDF]

Communications Biology
Obesity is a global pandemic that affects people of all ages. While behavioral, nutritional, and socioeconomic factors all contribute to weight gain, other factors in our immediate environment play an insidious role in the prevalence of obesity. Exposure
Sara Al Kassir, Théo Mercé, Laure M. Bourcier, Sandra Pedemay, Magalie Soares, Anja Knoll-Gellida, Patrick J. Babin   +6 more
doaj   +2 more sources

Subacute Exposure to Aldrin, Endosulfan and Lindane Differentially Alters Metabolic and Inflammatory Gene Expression in White and Brown Adipose Tissue of Male Rats. [PDF]

Cell Biochem Funct
ABSTRACT Persistent organic pollutants such as organochlorine pesticides (OCPs) have been implicated in obesity and metabolic dysfunction. As they bioaccumulate in adipose tissue, OCPs may act as obesogens, but in vivo evidence for aldrin, endosulfan and lindane is limited.
Boujanah NAM, Erdogan CS, Sumer E, Yakin C, Yilmaz B.   +4 more
europepmc   +2 more sources

New Insight Into Male Infertility: Deviation From Basic Tenets of Life. [PDF]

Oxid Med Cell Longev
Male reproductive health faces mounting concern as global sperm concentration (SC) has declined markedly, with evidence linking this trend to environmental and lifestyle factors rather than natural variability. In parallel, rising rates of obesity, diabetes, and hypertension point to shared mechanisms with infertility, particularly those rooted in diet.
Nasr-Esfahani MH, Naderi N, Tavalaee M, Razi M.   +3 more
europepmc   +2 more sources

Grandmaternal perinatal serum polychlorinated biphenyls and prevalence of obesity in adult daughters and granddaughters. [PDF]

Obesity (Silver Spring)
Abstract Objective We investigated in utero exposure to polychlorinated biphenyl (PCB) 138, PCB 153, and PCB 180 and obesity at reproductive age in a three‐generation human cohort, i.e., the Child Health and Development Studies. Methods We used logistic models to estimate associations of PCBs in grandmothers' (F0) archived perinatal serum with obesity ...
Cohn BA, Cirillo PM, La Merrill MA, Murphy CC, Hu X, Krigbaum NY.   +5 more
europepmc   +2 more sources

An optimized zebrafish obesogenic test protocol with an artificial intelligence-based analysis software for screening obesogens and anti-obesogens. [PDF]

Biol Methods Protoc
Abstract Obesity is defined as a disease in which abnormal excessive body fat accumulation causes adverse effects on health. One proposed contributing factor to the rise in obesity is the exposure to endocrine disruptors acting as obesogens.
Al Kassir S, Mercé T, Pedemay S, Bourcier LM, Soares M, Le Mentec H, Podechard N, Knoll-Gellida A, Babin PJ.   +8 more
europepmc   +5 more sources

Obesity and endocrine-disrupting chemicals

Endocrine Connections, 2021
Obesity is now a worldwide pandemic. The usual explanation given for the prevalence of obesity is that it results from consumption of a calorie dense diet coupled with physical inactivity.
Angelica Amorim Amato, Hailey Brit Wheeler, Bruce Blumberg   +2 more
doaj   +1 more source

Bisphenol A substitutes and obesity: a review of the epidemiology and pathophysiology

Frontiers in Endocrinology, 2023
The prevalence of obesity, a condition associated with increased health risks, has risen significantly over the past several decades. Although obesity develops from energy imbalance, its etiology involves a multitude of other factors.
Shane V. Varghese, Julianne M. Hall
doaj   +1 more source

Environmental Obesogens and Their Perturbations in Lipid Metabolism [PDF]

Environment & Health
Guibin Jiang, Qunfang Zhou, Qian S Liu
exaly   +2 more sources

Mechanisms of action, chemical characteristics, and model systems of obesogens

BMC Biomedical Engineering, 2020
There is increasing evidence for the role of environmental endocrine disrupting contaminants, coined obesogens, in exacerbating the rising obesity epidemic. Obesogens can be found in everyday items ranging from pesticides to food packaging.
Mallory D. Griffin, Sean R. Pereira, Megan K. DeBari, Rosalyn D. Abbott   +3 more
doaj   +1 more source

The obesogenic side of Genistein

Frontiers in Endocrinology, 2023
Genistein (GN) has been highly recommended for its medicinal properties like anticancer, antidiabetic, antihyperlipidemic, antiviral, and antioxidant activities among others. Recently, scientists realized that Genistein is an endocrine disruptor. It is an obesogen that interferes with the endocrine system causing obesity through many mechanisms like ...
Jia Xiang, Jia Xiang, Ronald Mlambo, Progress Dube, Oleen Machona, Ibrahim Shaw, Yimer Seid, Yongju He, Min Luo, Tingting Hong, Binsheng He, Wenhu Zhou, Wenhu Zhou, Songwen Tan, Songwen Tan   +14 more
openaire   +3 more sources