Obesogenic Dysregulation of Human Periprostatic Adipose Tissue Promotes the Viability of Prostate Cells and Reduces Their Sensitivity to Docetaxel and Cabazitaxel [PDF]
Medical SciencesBackground: Periprostatic adipose tissue (PPAT) has been shown to play a significant role in prostate cancer (PCa) development and progression. This relationship is further exacerbated by obesity, as PPAT-secreted factors increase PCa aggressiveness and ...
Mariana Feijó +9 more
doaj +2 more sources
EFSA Journal, 2023 On‐going projects of the team are currently dealing with microbiota, xenobiotics, endocrine‐disrupting chemicals (EDCs), obesity, inflammation and probiotics.
Ana López‐Moreno +3 more
doaj +2 more sources
Environmental Obesogens and Their Impact on Susceptibility to Obesity: New Mechanisms and Chemicals [PDF]
Endocrinology, 2020 The incidence of obesity has reached an all-time high, and this increase is observed worldwide. There is a growing need to understand all the factors that contribute to obesity to effectively treat and prevent it and associated comorbidities.
Riann Jenay Egusquiza, Bruce Blumberg
exaly +2 more sources
Environmental Determinants of Pediatric Obesity: An Epidemiological Review [PDF]
EpidemiologiaPediatric obesity represents an urgent public health concern, with rapidly increasing prevalence across all regions. While genetic susceptibility contributes significantly to interindividual variability in weight, the significant increase in obesity ...
Doha Hassan +3 more
doaj +2 more sources
Grandmaternal perinatal serum polychlorinated biphenyls and prevalence of obesity in adult daughters and granddaughters. [PDF]
Obesity (Silver Spring)Abstract Objective We investigated in utero exposure to polychlorinated biphenyl (PCB) 138, PCB 153, and PCB 180 and obesity at reproductive age in a three‐generation human cohort, i.e., the Child Health and Development Studies. Methods We used logistic models to estimate associations of PCBs in grandmothers' (F0) archived perinatal serum with obesity ...
Cohn BA +5 more
europepmc +2 more sources
Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop [PDF]
American Journal of Clinical Nutrition, 2023 Jerrold Heindel +2 more
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Environmental Obesogens and Their Perturbations in Lipid Metabolism [PDF]
Environ Health (Wash)Zhendong Sun, Qian S Liu, Qunfang Zhou
exaly +2 more sources
Obesity and endocrine-disrupting chemicals
Endocrine Connections, 2021 Obesity is now a worldwide pandemic. The usual explanation given for the prevalence of obesity is that it results from consumption of a calorie dense diet coupled with physical inactivity.
Angelica Amorim Amato +2 more
doaj +1 more source
Mechanisms of action, chemical characteristics, and model systems of obesogens
BMC Biomedical Engineering, 2020 There is increasing evidence for the role of environmental endocrine disrupting contaminants, coined obesogens, in exacerbating the rising obesity epidemic. Obesogens can be found in everyday items ranging from pesticides to food packaging.
Mallory D. Griffin +3 more
doaj +1 more source
Traffic-related air pollution and obesity formation in children: a longitudinal, multilevel analysis. [PDF]
, 2014 BackgroundBiologically plausible mechanisms link traffic-related air pollution to metabolic disorders and potentially to obesity. Here we sought to determine whether traffic density and traffic-related air pollution were positively associated with growth
Berhane, Kiros +9 more
core +8 more sources