Results 41 to 50 of about 2,244 (165)

Epigenetic Transgenerational Inheritance of the Effects of Obesogen Exposure

open access: yesFrontiers in Endocrinology, 2021
Obesity and metabolic disorders have become a worldwide pandemic affecting millions of people. Although obesity is a multifaceted disease, there is growing evidence supporting the obesogen hypothesis, which proposes that exposure to a subset of endocrine
Nicole Mohajer   +6 more
doaj   +1 more source

Obesity, adipose tissue, inflammation and update on obesity management [PDF]

open access: yes, 2014
Review[Abstract] Obesity is a serious, common and growing problem. Obesity can be defined as an excess of body fat. Its clinical management is complex and frequently unsuccessful.
Cordido, Fernando   +2 more
core   +2 more sources

Protective effect of Anoectochilus burmannicus extracts and its active compound, kinsenoside on adipocyte differentiation induced by benzyl butyl phthalate and bisphenol A

open access: yesScientific Reports, 2023
Benzyl butyl phthalate (BBP) and bisphenol-A (BPA) are obesogens that have been reported to be associated with obesity. Inhibition of their adipogenic activity could decrease the risk of obesity-related metabolic disorders.
Pensiri Buacheen   +8 more
doaj   +1 more source

Effect of obesity and metabolic syndrome on plasma oxysterols and fatty acids in human [PDF]

open access: yes, 2015
BACKGROUND: Obesity and the related entity metabolic syndrome are characterized by altered lipid metabolism and associated with increased morbidity risk for cardiovascular disease and cancer.
H., Guillou   +7 more
core   +2 more sources

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye   +6 more
wiley   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 2003-2018, June 2026.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt   +5 more
wiley   +1 more source

Mechanisms of obesogens and their impact on adipose tissue, hormones, and inflammation

open access: yesJournal of Medical Science
Obesity, a pervasive global health challenge influenced by intricate interplays of genetic, environmental, and behavioral factors, remains a critical concern affecting populations worldwide.
Taiwo Ogunjobi   +12 more
doaj   +1 more source

Exposure to Metal Mixtures and Childhood Adiposity: An Examination of Periods of Heightened Susceptibility Between Gestation and Late Childhood

open access: yesPediatric Obesity, Volume 20, Issue 12, December 2025.
ABSTRACT Introduction Childhood obesity is a public health concern. Studies have investigated the effects of metal mixtures on childhood obesity but none have identified periods of heightened susceptibility of exposure. We identified the periods by investigating the association of metal mixture, measured at four time points, with adiposity.
Janice M. Y. Hu   +8 more
wiley   +1 more source

Association Between Perfluoroalkyl Substance (PFAS) Exposure and Nonalcoholic Fatty Liver Disease in Korean Adults: Results From the KoNEHS 2018–2020: A Cross‐Sectional Study

open access: yesAmerican Journal of Industrial Medicine, Volume 68, Issue 7, Page 588-597, July 2025.
ABSTRACT Objectives Nonalcoholic fatty liver disease (NAFLD) is a major public health problem and the most common chronic liver disease today. In Korea, the prevalence and incidence of NAFLD are currently very high, causing a serious social burden. Perfluoroalkyl substances (PFAS) have been consistently implicated as a potential cause of NAFLD, but ...
Jisuk Yun, Young‐Sun Min
wiley   +1 more source

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