Results 41 to 50 of about 1,065 (167)

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, Volume 41, Issue 9, Page 709-729, September 2026.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source

Mechanisms of obesogens and their impact on adipose tissue, hormones, and inflammation

Journal of Medical Science
Obesity, a pervasive global health challenge influenced by intricate interplays of genetic, environmental, and behavioral factors, remains a critical concern affecting populations worldwide.
Taiwo Ogunjobi, Charles Omiyale, Tolulope Gbayisomore, Oluwatoyin Olofin, Patricia Nneji, Damilola Onikeku, Moses Oluwole, Somtochukwu Ezeano, Dayo Soleye, Dasola Fadipe, Samson Fakojo, Tobi Sulaiman, Rufus Ajayi   +12 more
doaj   +1 more source

Protective effect of Anoectochilus burmannicus extracts and its active compound, kinsenoside on adipocyte differentiation induced by benzyl butyl phthalate and bisphenol A

Scientific Reports, 2023
Benzyl butyl phthalate (BBP) and bisphenol-A (BPA) are obesogens that have been reported to be associated with obesity. Inhibition of their adipogenic activity could decrease the risk of obesity-related metabolic disorders.
Pensiri Buacheen, Jirarat Karinchai, Natchapon Kammasit, Piya Temviriyanukul, Chutikarn Butkinaree, Santi Watthana, Ariyaphong Wongnoppavich, Arisa Imsumran, Pornsiri Pitchakarn   +8 more
doaj   +1 more source

Epigenetic Transgenerational Inheritance of the Effects of Obesogen Exposure

Frontiers in Endocrinology, 2021
Obesity and metabolic disorders have become a worldwide pandemic affecting millions of people. Although obesity is a multifaceted disease, there is growing evidence supporting the obesogen hypothesis, which proposes that exposure to a subset of endocrine
Nicole Mohajer, Erika M. Joloya, Jeongbin Seo, Toshi Shioda, Bruce Blumberg, Bruce Blumberg, Bruce Blumberg   +6 more
doaj   +1 more source

Protocols for the development of the guidance on the risk assessment of PPP to non‐target arthropods, in‐soil organisms and non‐target terrestrial plants

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The present document defines the problem formulation, evidence needs and methodological approach agreed by the Environmental Risk Assessment Working Group and the EFSA Panel on Plant Protection Products and their Residues for the Tier 1 risk assessment of the terrestrial ecotoxicology guidance document.
European Food Safety Authority (EFSA), Pauline Adriaanse, Gertie Arts, Sandra Boline Lassen, Mark Brown, Pierre‐Francois Chaton, Matthias Fürst, Brecht Ingels, Silvia Pieper, Maj Rundlöf, Jose Paulo Sousa, Renske van Eekelen, Fernando Alvarez, Maria Arena, Gabriella Fait, Alessio Ippolito, Alberto Linguadoca, Laura Padovani, Csaba Szentes, Domenica Auteri   +19 more
wiley   +1 more source

Endocrine Disrupting Chemicals: An Occult Mediator of Metabolic Disease

Frontiers in Endocrinology, 2019
Endocrine disrupting chemicals (EDCs), a heterogeneous group of exogenous chemicals that can interfere with any aspect of endogenous hormones, represent an emerging global threat for human metabolism.
Olga Papalou, Eleni A. Kandaraki, George Papadakis, Evanthia Diamanti-Kandarakis   +3 more
doaj   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

Journal of Applied Toxicology, Volume 46, Issue 6, Page 2003-2018, June 2026.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt, Nathalie Struwe, Annika Jansson, Vesna Munic Kos, Maria Larsson, Jana M. Weiss   +5 more
wiley   +1 more source

Microbiota analysis for risk assessment of xenobiotic exposure and the impact on dysbiosis: identifying potential next‐generation probiotics

EFSA Journal, 2023
On‐going projects of the team are currently dealing with microbiota, xenobiotics, endocrine‐disrupting chemicals (EDCs), obesity, inflammation and probiotics.
Ana López‐Moreno, Philippe Langella, Rebeca Martín, Margarita Aguilera   +3 more
doaj   +1 more source

Exposure to Metal Mixtures and Childhood Adiposity: An Examination of Periods of Heightened Susceptibility Between Gestation and Late Childhood

Pediatric Obesity, Volume 20, Issue 12, December 2025.
ABSTRACT Introduction Childhood obesity is a public health concern. Studies have investigated the effects of metal mixtures on childhood obesity but none have identified periods of heightened susceptibility of exposure. We identified the periods by investigating the association of metal mixture, measured at four time points, with adiposity.
Janice M. Y. Hu, Michael M. Borghese, Mandy Fisher, Joseph M. Braun, Katherine M. Morrison, Mark R. Palmert, Linda Booij, Constadina Panagiotopoulos, Jillian Ashley‐Martin   +8 more
wiley   +1 more source

Obesogenic environment – intervention opportunities

Jornal de Pediatria, 2016
To evaluate environmental obesogenic-related factors, such as physical activity in neighborhoods and schools, nutritional behavior, and intervention programs.Critical analysis of literature with personal point of view from infant obesity experts and political advisors for public intervention.Although obesity is a public health problem affecting several
Fisberg, Mauro, Maximino, Priscila, Kain Berkovic, Juliana, Kovalskys, Irina   +3 more
openaire   +8 more sources