Results 51 to 60 of about 7,368,420 (284)

Subjective and Objective Career Success: A Gender Based Analysis of Career Outcomes

Journal of Research in Humanities and Social Science
This study investigates gender differences in performance by examining subjective and objective success among IT professionals. Subjective success refers to an individual's internal evaluation of career satisfaction, purpose, and fulfilment based on personal values and goals.
Dr. Megha Arya Dr. Megha Arya, Devyani Jain Devyani Jain   +1 more
openaire   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Modelling the influence of workaholism on career success: A PLS-SEM approach [PDF]

, 2022
Organizations characterized by a climate and culture of competition and overwork facilitate the emergence of the workaholism phenomenon, as they provide favorable conditions for employees to spend more time in the workplace.
Diogo, S., Santos, E., Gomes, P., Ratten, Vanessa, Eulália Santos, Ana Diogo, Patrícia Gomes, Vanessa Ratten   +7 more
core   +1 more source

The role of emotional quotients and adversity quotients in career success

Frontiers in Psychology, 2023
Career success has been considered equally important for both personal and organizational development. The purpose of the current study was to examine how trait emotional quotient (EQ) and adversity quotient (AQ) contribute to individuals’ objective ...
Yuyang Zhao, Biao Sang
doaj   +1 more source

The Career Decision-Making Adaptability Score: Exploration and validation of its predictive power for subjective and objective career success

International Journal for Educational and Vocational Guidance, 2022
AbstractThe study aims at validating the Career Decision-Making Adaptability Score (CDA Score) by investigating its predictive influence on objective and subjective career success, career adaptability, and psychological well-being over a 1-year period. Furthermore, the predictive influence of additional career decision-making strategies was scrutinized.
Katharina Ebner, Karsten Ingmar Paul
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Is Protean Career Attitude Beneficial for Both Employees and Organizations? Investigating the Mediating Effects of Knowing Career Competencies

Frontiers in Psychology, 2019
The aim of this study was to investigate the direct and indirect effects of protean career attitude on subjective and objective career success representing personal outcomes and task performance reflecting an organizational outcome.
Razia Sultana, Razia Sultana, Omer Farooq Malik   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source