Results 101 to 110 of about 82,731 (339)

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

CERVICAL CERCLAGE

Journal of Nepal Medical Association, 2003
A Rana, G Gurung, M singh, N Pradhan, R Jha   +4 more
doaj   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Pelatihan Pembuatan Media Pembelajaran Berbentuk Video Animasi 3d Dengan Karakter Diri Sendiri Menggunakan Aplikasi Loomie Dan Obs Untuk Meningkatkan Literasi Informasi Pada Guru Mgmp Matematika Smp Kota Jambi

, 2023
Gugun M. Simatupang, Husni Sabil, Mujahidawati Mujahidawati, Dewi Iriani, Febbry Romundza   +4 more
openalex   +2 more sources

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Maternal Morbidity Associated With A Successful Versus Failed Trial of Labour After A Previous Caesarean Section

Pakistan Armed Forces Medical Journal
Objective: To compare the maternal morbidity associated with a successful trial of labour after the previous scar versus a failed trial of labour after the previous scar and ending in repeat Caesarean section.
Beenish Rashid, Abida Ashraf, Mahpara Tariq, Abeera Choudry, Qurat ul Ain, Hira Shafqat   +5 more
doaj   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Comparison of Immediate Induction (Within 6 Hours) Versus Late Induction (After 24 Hours) in Terms of Mean PROM to Delivery Interval in Females Presenting with Term PROM

Journal of Rawalpindi Medical College, 2018
Background: To compare the immediate induction (within 06 hours) versus late induction (after 24 hours) in terms of mean pre-labour rupture of membranes (PROM) to delivery interval in females presenting with term PROM.
Kanwal Firdos, Maliha Sadaf, Farzana Kazmi   +2 more
doaj  

Frequency of Postpartum Depression Among Covid-19 Affected Mothers

Pakistan Armed Forces Medical Journal
Objective: To evaluate the frequency of Postpartum depression among COVID-19 affected mothers. Study Design: Comparative cross-sectional study. Place and Duration of Study: Obstetrics and Gynaecology Department of PEMH, Rawalpindi Pakistan, from Jun
Abeera Choudary, Faiqa Chugtai, Hira Shafqat, Asifa Siraj, Zainab Abbas, Maria Habib   +5 more
doaj   +1 more source