Results 121 to 130 of about 284,425 (312)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Non-linear discrete-time observer design by sliding mode
, 2007 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 09/02/2007.Research into observer design for non-linear discrete-time systems has produced many design methods.
Algarawi, Mohammed
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2012 Decentralised variable structure observers are proposed for a class of nonlinear time delay interconnected systems. The nonlinear interconnections are unknown and time delayed.
Shi, Peng +13 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2015 Hering (1964) hypothesized that the representation of a familiar object, which primarily includes its prototypical colour on the visual, conceptual and lexical domains may significantly influence how human observers organize the object’s chromatic ...
Adeyefa-Olasupo, Ifedayo-Emmanuel
core
, 2017 Behavioural scores for time out of shelter across 25min observations of Amphiprion crysopterus when observers are ...
Rocardo Beldade (8019674) +7 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An overview of model observers
, 2014 International audienceNowadays, model observers have been used more and more for the objective quality assessment of medical images. Model observers have been developed from signal known exactly (SKE) task to signal known statistically (SKS) task, from ...
Zhang, Lu +5 more
core +1 more source