Results 131 to 140 of about 284,425 (312)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Detecting and Correcting Election Fraud [PDF]
I examine the provision of free and fair elections using a decision-theoretic model in which election observers provide a noisy information signal concerning fraud.
Daniel Sutter
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2016 I present a simple variant of the Schrödinger cat meets Wigner's friend thought experiment. If you are shocked by it, you have not understood quantum physics (no words are missing from this sentence).
openaire +2 more sources
Computer based state observers magnet systems
reservedSi vuole fare un simulatore dove si testa come stimare lo stato di un magnete levitante(per effetto di un campo magnetico) usando computer ...
D'AURIA, GIUSEPPE
core
Strong detectability and observers
, 1983 Conditions are given for the existence of observers that estimate unmeasured outputs on the basis of partial information on the input and the state. The concepts of strong detectability and strong observability, introduced before in the literature for ...
Hautus, M.L.J., M.L.J. Hautus
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Optimal context-sensitive dynamic partial order reduction with observers
, 2019 Dynamic Partial Order Reduction (DPOR) algorithms are used in stateless model checking to avoid the exploration of equivalent execution sequences. DPOR relies on the notion of independence between execution steps to detect equivalence. Recent progress in
Isabel Márquez, Miguel +9 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source