Enteral absorption of octreotide [PDF]
The somatostatin octapeptide‐analogue, octreotide, is absorbed as intact peptide from the gastrointestinal (GI) tract. In situ absorption experiments in rats confirmed our recent intubation studies in human volunteers demonstrating that the peptide has preferential absorption sites in the small intestine.
Christoph Beglinger+4 more
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Use of Octreotide in the Acute Management of Bleeding Esophageal Varices [PDF]
Acute hemorrhage from esophageal varices is a medical emergency; despite early diagnosis and treatment the associated hospital mortality remains high.
Daniel C Sadowski
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Comparative analysis of adverse event profiles of lanreotide and octreotide in somatostatin-responsive endocrine and neoplastic diseases [PDF]
Lanreotide and Octreotide are used to treat various endocrine and neoplastic diseases. This study aims to compare the adverse event profiles of Lanreotide and Octreotide in somatostatin-responsive diseases using FAERS data.
Le Wang+3 more
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18F-AlF-NOTA-octreotide PET/CT and 3D printing technology for precision diagnosis and treatment of phosphaturic mesenchymal tumors in patients with tumor-induced osteomalacia: two case reports [PDF]
ObjectiveThis study aims to report the application of 18F-AlF-NOTA-Octreotide PET/CT and 3D printing technology in the diagnosis and treatment of phosphaturic mesenchymal tumors (PMT) in patients with tumor-induced osteomalacia (TIO).Case presentationA ...
Gang Zhao+10 more
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Use of octreotide for prevention of pancreatic leak after pancreatoduodenectomy: study progress [PDF]
The pancreatic leak after pancreaticoduodenectomy was one of the main causes of postoperative death, the rate of which remained high. Octreotide, an octapeptide somatostatin analogue, has been used in the prevention and treatment of postoperative ...
XU Yu, ZHANG Junfeng, HUA Rong
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Acromegaly is a condition most commonly diagnosed in the fifth decade of life and has numerous treatment options. In this regard, Mycapssa® is the first FDA-approved oral octreotide capsule for treating acromegaly, combining the efficacy of the ...
Charles P. Daniel+9 more
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A peptide inhibiting the release of growth hormone was originally detected accidentally during studies of the distribution of growth hormone–releasing factor in the hypothalamus of rats. This peptide, called somatostatin, proved to be a cyclic peptide consisting of 14 amino acids.
Lamberts, Steven W.J.+3 more
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Effect of Octreotide Injection on Postoperative Drainage After Neck Dissection: A Preliminary Report of a Prospective, Matched Case-Control Study [PDF]
Objectives Somatostatin inhibits lymph production and reduces lymph flow into the lymphatic duct. We hypothesized that octreotide, a long-acting somatostatin analog, would reduce drainage after neck dissection (ND) by reducing the overall lymphatic flow ...
Dongbin Ahn+3 more
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Octreotide in the treatment of acromegaly – the possibilities of high-dose therapy
Octreotide is a first-generation somatostatin analog that has been used for 40 years for the medical treatment of acromegaly, both after neurosurgical intervention and as first-line treatment.
I. A. Ilovayskaya
doaj +1 more source
complications following pancreatic surgery). Somatostatin analogues including octreotide have been shown to reduce pressure in the splanchnic circulation, an effect that was exploited in the management of variceal and nonvariceal hemorrhages. Despite a widespread therapeutic application, octreotide seems to be a safe drug free of major side effects ...
Beglinger C, Büchler Mw
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