Results 71 to 80 of about 22,517 (214)

New medical therapies on the horizon: oral octreotide

Pituitary, 2017
Somatostatin analog treatment is first line medical treatment in patients with acromegaly. This drug is currently mainly administered by monthly depot preparations of octreotide and lanreotide.
N. Biermasz
semanticscholar   +1 more source

Octreotide in hepatocellular carcinoma [PDF]

Gut, 1998
See article on page442 In this issue Kouroumalis et al (see page 442) report extended survival in patients with hepatocellular carcinoma (HCC) treated with octreotide, a somatostatin analogue. Somatostatin is a cyclic peptide consisting of 14 amino acids which regulates growth hormone release.
openaire   +3 more sources

Pasireotide Versus Octreotide in Acromegaly: A Head-to-Head Superiority Study

Journal of Clinical Endocrinology and Metabolism, 2014
Context: Biochemical control reduces morbidity and increases life expectancy in patients with acromegaly. With current medical therapies, including the gold standard octreotide long-acting-release (LAR), many patients do not achieve biochemical control ...
A. Colao, M. Bronstein, P. Freda, F. Gu, C. Shen, C. Shen, M. Gadelha, M. Fleseriu, A. V. D. Lely, A. Farrall, K. H. Reséndiz, Matthieu Ruffin, Yinmiao Chen, M. Sheppard   +13 more
semanticscholar   +1 more source

Pancreatic Panniculitis Without Pancreatopathy: A Rare Complication of Splenic Vein Stenting for Portal Hypertension in Myeloproliferative Syndrome

United European Gastroenterology Journal, EarlyView.
Eliza Butnaru, Solène Tran Van, Franck Brazier, Clara Yzet   +3 more
wiley   +1 more source

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 2070-2079, July 2025.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo, Ajay Madan, Christine T. Ferrara‐Cook, Deepak Dalvie, Lance Goulet, R. Scott Struthers, Alan S. Krasner   +6 more
wiley   +1 more source

Octreotide in variceal bleeding. [PDF]

Gut, 1994
Bleeding from oesophageal varices has a high death rate. Injection sclerotherapy is the most appropriate treatment but facilities for this are not always available. Balloon tamponade and vasoactive therapy may be used as stop gap measures. Somatostatin and octreotide are therapeutic candidates for the treatment of variceal bleeding and there are ...
openaire   +3 more sources

FIGO guideline on liver disease and pregnancy

International Journal of Gynecology &Obstetrics, Volume 170, Issue 1, Page 28-48, July 2025.
Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana, Virna Medina, Cynthia Maxwell, Ciara McCormick, Gloria Taliani, Ulrich Beuers, Deborah Money, Bo Jacobsson, Anil Kapur, Titus Beyuo, Francisco Ruiloba, Graeme Smith, Lina Bergman, Sharleen O'Reilly, Patrick O'Brien, Mark Hanson, Mary Rosser, Claudio Sosa, Sumaiya Adam, Valerie Guinto, Liona Poon, Fionnuala McAuliffe, Catherine Williamson, on behalf of the FIGO Committee on Impact of Pregnancy on Long‐term Health, FIGO Committee on Infections during Pregnancy and the FIGO Division of Maternal and Newborn Health   +24 more
wiley   +1 more source

Use of octreotide for the treatment of protein‐losing enteropathy in dogs: Retrospective study of 18 cases

Journal of Veterinary Internal Medicine
Background More than 50% of dogs with protein‐losing enteropathy (PLE) fail to respond to standard therapies. Octreotide, a somatostatin analogue, is used in cases of intestinal lymphangiectasia (IL) in humans with some success.
Sara A. Jablonski, Allison S. W. Mazepa, M. Katherine Tolbert   +2 more
doaj   +1 more source

Ketotic Hypoglycaemia Following Sleeve Gastrectomy

Clinical Endocrinology, Volume 103, Issue 1, Page 45-49, July 2025.
ABSTRACT Post‐bariatric surgery hypoglycaemia is typically mediated by hyperinsulinaemia, although the exact mechanisms are incompletely understood. Two cases of non‐insulin mediated, ketotic hypoglycaemia following sleeve gastrectomy are presented. After fasting for 40 and 65 h, respectively, both patients developed symptomatic hypoglycaemia, with ...
Jinwen He, Liza Phillips, Janelle Nisbet, Adam Morton   +3 more
wiley   +1 more source

Mifepristone Improves Octreotide Efficacy in Resistant Ectopic Cushing’s Syndrome

Case Reports in Endocrinology, 2016
A 30-year-old Caucasian man presented with severe Cushing’s syndrome (CS) resulting from ectopic adrenocorticotropin syndrome (EAS) from a metastatic pancreatic neuroendocrine tumor.
Andreas G. Moraitis, Richard J. Auchus
doaj   +1 more source