Results 51 to 60 of about 11,439 (266)

Mild heat stress promotes the differentiation of odontoblast-like MDPC-23 cells via yes-associated protein

open access: yesInternational Journal of Hyperthermia
Purpose Dentin hypersensitivity (DH) is a prevalent condition, but long-term effective treatments are scarce. Differentiation of odontoblast-like cells is promising for inducing tertiary dentinogenesis and ensuring sustained therapeutic efficacy against ...
Peiqi Liu   +9 more
doaj   +1 more source

Periodontitis treatment and microbiome in a patient with FAM20A mutation: Case study of 1.5 years

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Enamel‐renal‐gingival syndrome (ERGS) is an autosomal recessive disorder caused by mutations in the FAMily with sequence similarity 20A (FAM20A) gene, and is characterized by amelogenesis imperfecta, delayed or failed tooth eruption, and periodontitis.
John Rong Hao Tay   +2 more
wiley   +1 more source

Lithium Chloride Exerts Differential Effects on Dentinogenesis and Osteogenesis in Primary Pulp Cultures

open access: yesFrontiers in Dental Medicine, 2021
Wnt/β-catenin signaling is known to play essential roles in odontoblast differentiation and reparative dentin formation. Various Wnt activators including LiCl have been increasingly studied for their effectiveness to induce repair of the dentin-pulp ...
Anushree Vijaykumar, Mina Mina
doaj   +1 more source

Odontoblasts release exosomes to regulate the odontoblastic differentiation of dental pulp stem cells

open access: yesStem Cell Research & Therapy, 2023
Abstract Background Dental pulp stem cells (DPSCs) play a crucial role in dentin-pulp complex regeneration. Further understanding of the mechanism by which DPSCs remain in a quiescent state could contribute to improvements in the dentin-pulp complex and dentinogenesis. Methods
Xinghong Luo   +11 more
openaire   +3 more sources

Dental development in the tropical gar (Atractosteus tropicus) and the evolution of vertebrate dentitions

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Dentitions have diversified enormously during vertebrate evolution, involving reductions, modifications, or allocations to prey seizing and processing regions. A combination of ancient and novel features related to dental and oropharyngeal apparatuses is found in extant lineages of non‐teleost fishes, such as the gars.
Anna Pospisilova   +4 more
wiley   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki   +6 more
wiley   +1 more source

High pH-Sensitive Store-Operated Ca2+ Entry Mediated by Ca2+ Release-Activated Ca2+ Channels in Rat Odontoblasts

open access: yesFrontiers in Physiology, 2018
Odontoblasts play a crucial role in dentin formation and sensory transduction following the application of stimuli to the dentin surface. Various exogenous and endogenous stimuli elicit an increase in the intracellular free calcium concentration ([Ca2+]i)
Maki Kimura   +7 more
doaj   +1 more source

Cytotoxicity, Differentiation, and Biocompatibility of Root-End Filling: A Comprehensive Study

open access: yesBiomimetics, 2023
Assessing the biocompatibility of endodontic root-end filling materials through cell line responses is both essential and of utmost importance.
Ignacio Jimenez-Bueno   +7 more
doaj   +1 more source

In Vitro Evaluation of Novel Calcium Silicate‐Based and Resin‐Modified Calcium Silicate Materials: Cytocompatibility and Mineralization Potential on Human Dental Pulp Stem Cells for Pulp Repair

open access: yesMicroscopy Research and Technique, EarlyView.
This study demonstrates that Biodentine XP exhibits superior cytocompatibility, promotes odontogenic differentiation, and enhances mineralization in human dental pulp stem cells, supporting its use in regenerative endodontics. Resin‐modified materials showed lower bioactivity, highlighting the importance of material composition in pulp therapy outcomes.
Francisco Javier Rodríguez‐Lozano   +5 more
wiley   +1 more source

Culture medium modulates the behaviour of human dental pulp-derived cells: Technical Note [PDF]

open access: yesEuropean Cells & Materials, 2006
In vitro approaches have extensively been developed to study reparative dentinogenesis. While dental pulp is a source of unidentified progenitors able to differentiate into odontoblast-like cells, we investigated the effect of two media; MEM (1.8mM Ca ...
S Lopez-Cazaux   +5 more
doaj  

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