BMP Signaling Pathway in Dentin Development and Diseases
Cells, 2022 BMP signaling plays an important role in dentin development. BMPs and antagonists regulate odontoblast differentiation and downstream gene expression via canonical Smad and non-canonical Smad signaling pathways.
Mengmeng Liu +3 more
doaj +1 more source
Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration
Frontiers in Bioengineering and Biotechnology, 2021 Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which ...
Jiahui Fu +8 more
doaj +1 more source
TWIST1 Promotes the Odontoblast-like Differentiation of Dental Stem Cells [PDF]
, 2011 Stem cells derived from the dental pulp of extracted human third molars (DPSCs) have the potential to differentiate into odontoblasts, osteoblasts, adipocytes, and neural cells when provided with the appropriate conditions.
I. Maciejewska +11 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2021 Proper differentiation of odontoblasts is crucial for the development of tooth roots. Previous studies have reported the osteogenic/odontogenic potential of pre-odontoblasts during root odontoblast differentiation.
Ran Zhang +8 more
doaj +1 more source
Odontoblast-like Cytodifferentiation of Dental Stem Cells: A Review [PDF]
, 2020 Dental problems are common in human populations. Traditional treatments are focused on managing caries, soft tissue impairments, functional defects, poor aesthetics, digestive disorders and alveolar bone resorption. During the last two decades, basic and
Matin, Maryam M, Babaki, Danial
core +1 more source
The BMP and FGF pathways reciprocally regulate odontoblast differentiation
, 2022 Previous studies demonstrated that the exposure of primary dental pulp (DP) cultures to fibroblast growth factor 2 (FGF2) between days 3–7 exerted significant and long-lasting stimulatory effects on odontoblast differentiation and Dspp expression.
Karo Parsegian (13028274)
core +1 more source
Differentially Expressed Protein Profile of Human Dental\ud Pulp Cells in the Early Process of Odontoblast-like\ud Differentiation In Vitro [PDF]
, 2008 Dental pulp cells (DPCs) are capable of differentiating\ud into odontoblasts that secrete reparative dentin after\ud pulp injury. The molecular mechanisms governing reparative\ud dentinogenesis are yet to be fully understood.\ud Here we investigated the ...
Wu, Liping +6 more
core +1 more source
Suberoylanilide Hydroxamic Acid Enhances Odontoblast Differentiation
, 2012 Previous studies have shown that histone deacetylase (HDAC) inhibitors stimulate osteoblast differentiation in vitro and bone formation in vivo. However, the effects of HDAC inhibitors on odontoblasts have not been elucidated.
Park, H.-J. +8 more
core +1 more source
Cellular Dynamics and Dentine Bridge Formation Following Direct Pulp Capping With MTA and Biodentine in a Murine Model. [PDF]
Int Endod JABSTRACT Aim Formation of a mineralized dentine bridge is the hallmark of successful direct pulp capping (DPC). Mineral trioxide aggregate (MTA) and Biodentine are widely used capping materials, but in vivo evidence comparing their regenerative potential remains inconclusive. This study used a controlled murine model to compare dentine bridge formation
Sajdeya A +4 more
europepmc +2 more sources
Cell Differentiation and Replication during Postnatal Development of the Murine First Molar
Biology, 2021 Various signaling molecular pathways are involved in odontogenesis to promote cellular replication and differentiation. Tooth formation is controlled mainly by epithelial–mesenchymal interactions.
Rudi Balzano +2 more
doaj +1 more source