Results 11 to 20 of about 861,821 (161)

Increasing Odontoblast-like Differentiation from Dental Pulp Stem Cells through Increase of β-Catenin/p-GSK-3β Expression by Low-Frequency Electromagnetic Field

Biomedicines, 2021
Odontoblasts produce proteins that form the dentinal extracellular matrix, which can protect the dental pulp from external stimuli and is required for tooth regeneration.
Han-Moi Lim, Myeong-Hyun Nam, Yu-Mi Kim, Young-Kwon Seo   +3 more
doaj   +2 more sources

Natural Bioactive Epigallocatechin-Gallate Promote Bond Strength and Differentiation of Odontoblast-like Cells [PDF]

Biomimetics, 2023
The (-)-Epigallocatechin-gallate (EGCG) metabolite is a natural polyphenol derived from green tea and is associated with antioxidant, biocompatible, and anti-inflammatory effects. Objective: To evaluate the effects of EGCG to promote the odontoblast-like
Rene Garcia-Contreras, Patricia Alejandra Chavez-Granados, Carlos Alberto Jurado, Benjamin Aranda-Herrera, Kelvin I. Afrashtehfar, Hamid Nurrohman   +5 more
doaj   +4 more sources

Mild heat stress promotes the differentiation of odontoblast-like MDPC-23 cells via yes-associated protein

International Journal of Hyperthermia
Purpose Dentin hypersensitivity (DH) is a prevalent condition, but long-term effective treatments are scarce. Differentiation of odontoblast-like cells is promising for inducing tertiary dentinogenesis and ensuring sustained therapeutic efficacy against ...
Peiqi Liu, Zhen Li, Hui Zhang, Yijie Wang, Yuxin Liao, Yi Guo, Chenxu Wang, Yuanwu Zou, Rui Zou, Lin Niu   +9 more
doaj   +2 more sources

Odontoblast-like differentiation and mineral formation of pulpsphere derived cells on human root canal dentin in vitro [PDF]

Head & Face Medicine, 2017
Background The revitalization or regeneration of the dental pulp is a preferable goal in current endodontic research. In this study, human dental pulp cell (DPC) spheres were applied to human root canal samples to evaluate their potential adoption for ...
Jörg Neunzehn, Sandra Pötschke, Christian Hannig, Hans-Peter Wiesmann, Marie-Theres Weber   +4 more
doaj   +2 more sources

Deferoxamine-Induced Migration and Odontoblast Differentiation via ROS-Dependent Autophagy in Dental Pulp Stem Cells

Cellular Physiology and Biochemistry, 2017
Background/Aims: As a vital degradation and recycling system, autophagy plays an essential role in regulating the differentiation of stem cells. We previously showed that iron chelator deferoxamine (DFO) could promote the repair ability of dental pulp ...
Xuan Wang, Tian Tian Wu, Long Jiang, Du Rong, Ya Qin Zhu   +4 more
doaj   +2 more sources

Identification of dentinogenic cell-specific surface antigens in odontoblast-like cells derived from adult dental pulp

Stem Cell Research & Therapy, 2019
Background Odontoblast is a unique progenitor that plays a role in dentin formation. So far, the dentinogenic differentiation of dental pulp stem cells and the role of surface molecules of odontoblasts in dentinogenesis are not well known yet.
Kyung-Jung Kang, Chun-Jeih Ryu, Young-Joo Jang   +2 more
doaj   +2 more sources

In vitro reparative dentin: a biochemical and morphological study [PDF]

European Journal of Histochemistry, 2013
In this study, starting from human dental pulp cells cultured in vitro, we simulated reparative dentinogenesis using a medium supplemented with different odontogenic inductors.
G. Teti, V. Salvatore, A. Ruggeri, L. Manzoli, M. Gesi, G. Orsini, M. Falconi   +6 more
doaj   +2 more sources

Mouse-induced pluripotent stem cells differentiate into odontoblast-like cells with induction of altered adhesive and migratory phenotype of integrin.

PLoS ONE, 2013
Methods for differentiating induced pluripotent stem (iPS) cells into odontoblasts generally require epithelial-mesenchymal interactions. Here, we sought to characterize the cells produced by a 'hanging drop' technique for differentiating mouse iPS cells
Nobuaki Ozeki, Makio Mogi, Rie Kawai, Hideyuki Yamaguchi, Taiki Hiyama, Kazuhiko Nakata, Hiroshi Nakamura   +6 more
doaj   +2 more sources

Odontoblast-Like Cells Differentiated from Dental Pulp Stem Cells Retain Their Phenotype after Subcultivation [PDF]

International Journal of Cell Biology, 2018
Odontoblasts, the main cell type in teeth pulp tissue, are not cultivable and they are responsible for the first line of response after dental restauration.
Paula A. Baldión, Myriam L. Velandia-Romero, Jaime E. Castellanos   +2 more
doaj   +2 more sources

Chromatin Accessibility Predetermines Odontoblast Terminal Differentiation

Frontiers in Cell and Developmental Biology, 2021
Embryonic development and stem cell differentiation are orchestrated by changes in sequential binding of regulatory transcriptional factors to their motifs.
Qian Zhang, Zhen Huang, Huanyan Zuo, Yuxiu Lin, Yao Xiao, Yanan Yan, Yu Cui, Chujiao Lin, Fei Pei, Zhi Chen, Huan Liu, Huan Liu   +11 more
doaj   +1 more source