Results 21 to 30 of about 861,821 (161)

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]

Cell Prolif
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Zeng W, Lin Y, Gao Y, Huang D, Li Y, Ruan H, Yuan G, Liu H, Chen Z.   +8 more
europepmc   +2 more sources

Lithium Chloride Exerts Differential Effects on Dentinogenesis and Osteogenesis in Primary Pulp Cultures

Frontiers in Dental Medicine, 2021
Wnt/β-catenin signaling is known to play essential roles in odontoblast differentiation and reparative dentin formation. Various Wnt activators including LiCl have been increasingly studied for their effectiveness to induce repair of the dentin-pulp ...
Anushree Vijaykumar, Mina Mina
doaj   +1 more source

Role of connexin 43 in odontoblastic differentiation and structural maintenance in pulp damage repair

International Journal of Oral Science, 2021
Dental pulp can initiate its damage repair after an injury of the pulp–dentin complex by rearrangement of odontoblasts and formation of newly differentiated odontoblast-like cells.
Jiaxin Yin, Jue Xu, Ran Cheng, Meiying Shao, Yuandong Qin, Hui Yang, Tao Hu   +6 more
doaj   +1 more source

Silencing VEGFR-2 Hampers Odontoblastic Differentiation of Dental Pulp Stem Cells

Frontiers in Cell and Developmental Biology, 2021
Dental pulp stem cells (DPSCs) are a source of postnatal stem cells essential for maintenance and regeneration of dentin and pulp tissues. Previous in vivo transplantation studies have shown that DPSCs are able to give rise to odontoblast-like cells ...
Kajohnkiart Janebodin, Kajohnkiart Janebodin, Kajohnkiart Janebodin, Rakchanok Chavanachat, Aislinn Hays, Aislinn Hays, Aislinn Hays, Morayma Reyes Gil   +7 more
doaj   +1 more source

EFFECT OF MATERNAL VITAMIN D3 DEFICIENCY ON DENTINOGENESIS IN RATS (EXPERIMENTAL STUDY) [PDF]

Alexandria Dental Journal, 2022
Introduction: Vitamin D3 insufficiency has become a severe health problem that affects more than one billion people worldwide. Maternal vitamin D3 deficiency can induce dentin defects during tooth development.
Khadiga Kawana, Hossam eldin moustafa, Amira elnozahy, Ahmed Saleh   +3 more
doaj   +1 more source

Isolation and Differentiation of Adipose-Derived Stem Cells into Odontoblast-Like Cells: A Preliminary In Vitro Study [PDF]

, 2021
Objective: The aim of present study was to isolate and differentiate human adipose-derived stem cells (ASCs) into odontoblast-like cells. Materials and Methods: In this experimental study, human adipose tissues were taken from the buccal fat pad of ...
Abbasali Khademi, Khazaei, M., Paul M. H. Dummer, Khazaei, Saber, Mohammad Hossein Nasr Esfahani, Dummer, Paul MH, Khademi, A., Mozafar Khazaei, Nekoofar, M. H., Khazaei, Mozafar, Dummer, P. M. H., Khademi, Abbasali, Nekoofar, Mohammad Hossein, Mohammad Hossein Nekoofar, Nasr Esfahani, Mohammad Hossein, Saber Khazaei, Khazaei, S., Esfahani, M. H. N.   +17 more
core   +2 more sources

Cytotoxicity, Differentiation, and Biocompatibility of Root-End Filling: A Comprehensive Study

Biomimetics, 2023
Assessing the biocompatibility of endodontic root-end filling materials through cell line responses is both essential and of utmost importance.
Ignacio Jimenez-Bueno, Rene Garcia-Contreras, Benjamin Aranda-Herrera, Hiroshi Sakagami, Christian Andrea Lopez-Ayuso, Hiroshi Nakajima, Carlos A. Jurado, Hamid Nurrohman   +7 more
doaj   +1 more source

CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts

Frontiers in Cell and Developmental Biology, 2021
Dentin, which composes most of the tooth structure, is formed by odontoblasts, long-lived post-mitotic cells maintained throughout the entire life of the tooth. In mature odontoblasts, however, cellular activity is significantly weakened.
Yeoung-Hyun Park, Yeoung-Hyun Park, Chul Son, You-Mi Seo, Yoon Seon Lee, Alix Har, Joo-Cheol Park, Joo-Cheol Park   +7 more
doaj   +1 more source

DataSheet1_Chromatin Accessibility Predetermines Odontoblast Terminal Differentiation.docx

, 2021
Embryonic development and stem cell differentiation are orchestrated by changes in sequential binding of regulatory transcriptional factors to their motifs.
Yanan Yan (9184706), Huan Liu (281351), Zhi Chen (222749), Yao Xiao (227567), Yu Cui (160305), Zhen Huang (58276), Yuxiu Lin (11753159), Chujiao Lin (11753162), Huanyan Zuo (11753156), Qian Zhang (49333), Fei Pei (542729)   +10 more
core   +1 more source

FOXO3a promotes odontoblast differentiation in human dental pulp cells in coordination with RUNX2 [PDF]

Journal of Applied Oral Science
Introduction Forkhead box O3a (FOXO3a) is a stress-responsive transcription factor involved in cellular differentiation across multiple tissues.
Su-Kyung Son, Jung-Sun Moon, Na-Ri Jung, Jee-Hae Kang, Bin-Na Lee, Sun-Hun Kim, Min-Seok Kim   +6 more
doaj   +2 more sources