CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts
Frontiers in Cell and Developmental Biology, 2021 Dentin, which composes most of the tooth structure, is formed by odontoblasts, long-lived post-mitotic cells maintained throughout the entire life of the tooth. In mature odontoblasts, however, cellular activity is significantly weakened.
Yeoung-Hyun Park +7 more
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Presence of matrix vesicles in the body of odontoblasts and in the inner third of dentinal tissue: A scanning electron microscopyc study [PDF]
, 2013 Objectives: The aim of this report is to present the results of a scanning electron microscopic study on the presence of matrix vesicles (MVs) found in human dentine.
Maricela Garcés‐Ortíz +2 more
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Potassium Currents Activated by Depolarization in Odontoblasts [PDF]
Frontiers in Physiology, 2017 Increased intracellular free Ca2+ concentrations elicit plasma membrane depolarization, which leads to the activation of K+ currents. However, the precise properties of K+ currents activated by depolarization in odontoblasts remain to be elucidated.
Yuki Kojima +6 more
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Membrana preformativa: Unveiling the unexplored facets of dental development [PDF]
Journal of Oral Biology and Craniofacial ResearchAim: Odontogenesis is a complex and highly regulated biological process that involves a range of molecular mechanisms. Among these, Ki67 and Cyclin D1 are crucial cell cycle regulators that play pivotal roles in controlling cell proliferation during ...
Sakshi Sikaria +3 more
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FAM20C Functions Intracellularly Within Both Ameloblasts and Odontoblasts In Vivo [PDF]
, 2013 FAM20C, also known as Golgi casein kinase (G‐CK), is proposed to be the archetype for a family of secreted kinases that phosphorylate target proteins in the Golgi and in extracellular matrices, but FAM20C serving an extracellular function is ...
Shih‐Kai Wang +3 more
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Odontoblasts or odontocytes, expression of stem cells markers and differentiation markers among human adult odontoblasts [PDF]
Saudi Dental JournalObjective: Despite that, the odontoblasts of the dental pulp are considered a terminally differentiated type of cell. We were interested in investigating if they express any embryonic, mesenchymal, or neural stem cell markers, along with other ...
Heba Alzer, Firas Alsoleihat
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Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation [PDF]
Frontiers in Physiology, 2015 The penetration of cariogenic oral bacteria into enamel and dentin during the caries process triggers an immune/inflammatory response in the underlying pulp tissue, the reduction of which is considered a prerequisite to dentinogenesis-based pulp ...
Jean-Christophe eFARGES +15 more
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CREB3L1 deficiency impairs odontoblastic differentiation and molar dentin deposition partially through the TMEM30B [PDF]
International Journal of Oral ScienceOdontoblasts are primarily responsible for synthesizing and secreting extracellular matrix proteins, which are crucial for dentinogenesis. Our previous single-cell profile and RNAscope for odontoblast lineage revealed that cyclic adenosine monophosphate ...
Yuanyuan Li +8 more
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Role of the Demethylase AlkB Homolog H5 in the Promotion of Dentinogenesis
Frontiers in Physiology, 2022 Dentinogenesis is a key process in tooth formation and is regulated by a series of pre- and post-transcriptional regulations. N6-methyl-adenosine (m6A), which is the most prevalent internal chemical modification that can be removed by the RNA demethylase
Cheng Tian +12 more
doaj +1 more source
Frontiers in Dental Medicine, 2022 Dental caries is the most common chronic disease in children and adults worldwide. The complex etiology of dental caries includes environmental factors as well as host genetics, which together contribute to inter-individual variation in susceptibility ...
Mairobys Socorro +10 more
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