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Plasma Membrane Ca2+–ATPase in Rat and Human Odontoblasts Mediates Dentin Mineralization [PDF]

open access: goldBiomolecules, 2021
Intracellular Ca2+ signaling engendered by Ca2+ influx and mobilization in odontoblasts is critical for dentinogenesis induced by multiple stimuli at the dentin surface.
Maki Kimura   +9 more
doaj   +2 more sources

Odontoblasts in Equine Hypsodont Teeth—How They Cope with Permanent Occlusal Wear [PDF]

open access: yesAnimals
Horses’ hypsodont (high-crowned) teeth face permanent dental wear. This is compensated for by a continuous eruption, which requires a high adaptability of odontoblasts; otherwise, the dental pulp would be exposed.
Laura Beate Heilen   +4 more
doaj   +2 more sources

Odontoblasts in health and disease with an additional note on its three-Dimensional histological perspective

open access: diamondJournal of the Scientific Society, 2023
Teeth are considered to be the prime organs for mastication, speech, and esthetics. The basic structure of tooth involves enamel, dentin, and pulp. Each of these is formed by specialized structures during the various phases of tooth development.
Sandhya Tamgadge   +4 more
doaj   +2 more sources

Odontoblast [PDF]

open access: hybrid, 2020
National Cancer Institute
openalex   +2 more sources

Membrana preformativa: Unveiling the unexplored facets of dental development [PDF]

open access: yesJournal of Oral Biology and Craniofacial Research
Aim: Odontogenesis is a complex and highly regulated biological process that involves a range of molecular mechanisms. Among these, Ki67 and Cyclin D1 are crucial cell cycle regulators that play pivotal roles in controlling cell proliferation during ...
Sakshi Sikaria   +3 more
doaj   +2 more sources

Pericytes Are Odontoblast Progenitor Cells Depending on ER Stress. [PDF]

open access: hybridJ Dent Res
Ouchi T   +10 more
europepmc   +2 more sources

CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts

open access: yesFrontiers in Cell and Developmental Biology, 2021
Dentin, which composes most of the tooth structure, is formed by odontoblasts, long-lived post-mitotic cells maintained throughout the entire life of the tooth. In mature odontoblasts, however, cellular activity is significantly weakened.
Yeoung-Hyun Park   +7 more
doaj   +1 more source

Role of the Demethylase AlkB Homolog H5 in the Promotion of Dentinogenesis

open access: yesFrontiers in Physiology, 2022
Dentinogenesis is a key process in tooth formation and is regulated by a series of pre- and post-transcriptional regulations. N6-methyl-adenosine (m6A), which is the most prevalent internal chemical modification that can be removed by the RNA demethylase
Cheng Tian   +12 more
doaj   +1 more source

Deficiency of Mineralization-Regulating Transcription Factor Trps1 Compromises Quality of Dental Tissues and Increases Susceptibility to Dental Caries

open access: yesFrontiers in Dental Medicine, 2022
Dental caries is the most common chronic disease in children and adults worldwide. The complex etiology of dental caries includes environmental factors as well as host genetics, which together contribute to inter-individual variation in susceptibility ...
Mairobys Socorro   +10 more
doaj   +1 more source

circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046

open access: yesFrontiers in Physiology, 2022
circular RNAs (circRNAs) is a broad and diverse endogenous subfamily of non-coding RNAs, regulating the gene expression by acting as a microRNA (miRNA) sponge.
Yue Zhang   +3 more
doaj   +1 more source

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