Results 21 to 30 of about 9,236 (227)

Case Report: A Novel COL1A1 Missense Mutation Associated With Dentineogenesis Imperfecta Type I

open access: yesFrontiers in Genetics, 2021
Background: Osteogenesis imperfecta (OI) is a clinical and genetic disorder that results in bone fragility, blue sclerae and dentineogenesis imperfecta (DGI), which is mainly caused by a mutation in the COL1A1 or COL1A2 genes, which encode type I ...
Yuting Zeng   +7 more
doaj   +1 more source

Exostosin 1 is expressed in human odontoblasts [PDF]

open access: yes, 2017
Objective: Dental pulp is soft connective tissue maintaining the vitality of the tooth, while odontoblasts form the dentin. Our earlier DNA microarray analysis revealed expression of putative tumour suppressor exostosin 1 (EXT-1) in odontoblasts.
Tjaderhane, Leo   +9 more
core   +1 more source

High pH-Sensitive Store-Operated Ca2+ Entry Mediated by Ca2+ Release-Activated Ca2+ Channels in Rat Odontoblasts

open access: yesFrontiers in Physiology, 2018
Odontoblasts play a crucial role in dentin formation and sensory transduction following the application of stimuli to the dentin surface. Various exogenous and endogenous stimuli elicit an increase in the intracellular free calcium concentration ([Ca2+]i)
Maki Kimura   +7 more
doaj   +1 more source

Intercellular odontoblast communication via ATP mediated by pannexin-1 channel and phospholipase C-coupled receptor activation.

open access: yesFrontiers in Physiology, 2015
Extracellular ATP released via pannexin-1 channels, in response to the activation of mechanosensitive-TRP channels during odontoblast mechanical stimulation, mediates intercellular communication among odontoblasts in dental pulp slice preparation ...
Masaki eSato   +7 more
doaj   +1 more source

Dentin defects caused by a Dspp −1 frameshift mutation are associated with the activation of autophagy

open access: yesScientific Reports, 2023
Dentin sialophosphoprotein (DSPP) is primarily expressed by differentiated odontoblasts (dentin-forming cells), and transiently expressed by presecretory ameloblasts (enamel-forming cells).
Tian Liang   +9 more
doaj   +1 more source

Influence of Hydrogen Peroxide on Mineralization in Dental Pulp Cells: A Systematic Review

open access: yesFrontiers in Dental Medicine, 2021
Background: Dental bleaching agents show the ability to permeate through dental hard tissues, which may lead to pulp tissue changes. This systematic review (PROSPERO register: CRD42020213767) is aimed at understanding the effects of bleaching agents on ...
Alexandre Henrique dos Reis-Prado   +7 more
doaj   +1 more source

A Novel Method to Isolate Odontoblasts from Rat Incisor [PDF]

open access: yes, 2000
Historically, odontoblasts have been isolated from rat incisor using a surgical curette to separate these cells from the dentin. Isolation of odontoblasts using this approach typically resulted in cells with membrane properties that made the application ...
Berry, J. E.   +3 more
core   +1 more source

Evaluation of nano-hydroxyapatite application on fluorosed and nonfluorosed dentinal surface: A scanning electron microscope study

open access: yesSaudi Journal of Oral Sciences, 2023
Introduction: Although there are many desensitizing medications on the market with promising results, their therapeutic advantages are sometimes fleeting or diminished over time since they might be gradually destroyed by consistent tooth brushing or ...
Kharidhi Laxman Vandana   +2 more
doaj   +1 more source

Physiologic dentin regeneration: its past, present, and future perspectives

open access: yesFrontiers in Physiology, 2023
Regenerative dentistry has rapidly progressed since the advancement of stem cell biology and material science. However, more emphasis has been placed on the success of tissue formation than on how well the newly generated tissue retains the original ...
Myungjin Lee   +3 more
doaj   +1 more source

Effect of medium or high concentrations of in-office dental bleaching gel on the human pulp response in the mandibular incisors [PDF]

open access: yesRestorative Dentistry & Endodontics, 2023
ObjectivesThe present study evaluated the pulp response of human mandibular incisors subjected to in-office dental bleaching using gels with medium or high concentrations of hydrogen peroxide (HP).Materials and MethodsThe following groups were compared ...
Douglas Augusto Roderjan   +6 more
doaj   +1 more source

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