Results 21 to 30 of about 14,750 (276)

Three-dimensional Imaging Reveals New Compartments and Structural Adaptations in Odontoblasts [PDF]

Journal of dentistry research, 2015
In organized tissues, the precise geometry and the overall shape are critical for the specialized functions that the cells carry out. Odontoblasts are major matrix-producing cells of the tooth and have also been suggested to participate in sensory ...
M. Shahidi, J. Křivánek, Nina Kaukua, P. Ernfors, L. Hladík, V. Košťál, S. Masich, A. Hampl, V. Chubanov, Thomas Gudermann, Roman A. Romanov, Tibor Harkany, Tibor Harkany, Igor Adameyko, Igor Adameyko, Kaj Fried   +15 more
semanticscholar   +2 more sources

Potential role of odontoblasts in the innate immune response of the dental pulp

Dental Journal, 2008
Background: Odontoblasts are the cells lining of tooth’s hard structure at the dentin-pulp border, which become the first cells encountered oral microorganisms entering dentin.
Tetiana Haniastuti
doaj   +2 more sources

TRPA1 and TRPV4 Activation in Human Odontoblasts Stimulates ATP Release

Journal of dentistry research, 2014
The mechanism of pain in dentine hypersensitivity is poorly understood but proposed to result from the activation of dental sensory neurons in response to dentinal fluid movements.
O. Egbuniwe, S. Grover, A. Duggal, A. Mavroudis, M. Yazdi, T. Renton, L. Silvio, A. Grant   +7 more
semanticscholar   +2 more sources

Akt-GSK3β-mPTP pathway regulates the mitochondrial dysfunction contributing to odontoblasts apoptosis induced by glucose oxidative stress

Cell Death Discovery, 2022
Diabetes Mellitus can cause dental pulp cells apoptosis by oxidative stress, and affect the integrity and function of dental pulp tissue. Mitochondria are the main attack targets of oxidative stress and have a critical role in apoptosis. However, whether
Danni Wu, Liya Yan, ChuChu Zheng, Xuekun Ren, Yihuai Pan, Sheng-guang Huang, Li-Qun Pan, Zong-Shu Li   +7 more
semanticscholar   +1 more source

Nanofibrous topography-driven altered responsiveness to Wnt5a mediates the three-dimensional polarization of odontoblasts

Materials Today Bio, 2022
Cell differentiation with the proper three-dimensional (3-D) structure is critical for cells to carry out their cellular functions in tissues. Odontoblasts derived from neural crest cells are elongated and polarized with the cell process, which is ...
S. Rahman, W. Kim, S. Chung, K. Woo
semanticscholar   +1 more source

Radiographic and histopathologic outcomes of immature dog teeth with apical periodontitis after revascularization using propolis. An in vivo study

Saudi Endodontic Journal, 2020
Introduction: This study aimed to assess the radiographic and histopathologic outcomes of immature dog teeth with apical periodontitis after revascularization using propolis.
Nelly Abdelsalam, Ashraf M Abu-Seida, Dalia Fayyad, Hossam Tawfik   +3 more
doaj   +1 more source

Gα_s-Coupled CGRP Receptor Signaling Axis from the Trigeminal Ganglion Neuron to Odontoblast Negatively Regulates Dentin Mineralization

Biomolecules, 2022
An inflammatory response following dental pulp injury and/or infection often leads to neurogenic inflammation via the axon reflex. However, the detailed mechanism underlying the occurrence of the axon reflex in the dental pulp remains unclear.
Natsuki Saito, Maki Kimura, Takehito Ouchi, Tatsuya Ichinohe, Yoshiyuki Shibukawa   +4 more
doaj   +1 more source

Transforming Growth Factor-β Signaling Regulates Tooth Root Dentinogenesis by Cooperation With Wnt Signaling

Frontiers in Cell and Developmental Biology, 2021
Proper differentiation of odontoblasts is crucial for the development of tooth roots. Previous studies have reported the osteogenic/odontogenic potential of pre-odontoblasts during root odontoblast differentiation.
Ran Zhang, Ran Zhang, Jingting Lin, Yang Liu, Shurong Yang, Qi He, Liang Zhu, Xiao Yang, Guan Yang   +8 more
doaj   +1 more source

Use of calcium hydroxyapatite and growth factors in endodontic therapy [PDF]

Vojnosanitetski Pregled, 2021
Background/Aim. Hydroxyapatite (HAp) is one of the most commonly used calcium phosphate bioceramics with osteoconductive properties. Growth factors are capable of directly inducing morphological and functional differentiation of neodontoblasts.
Mitić Aleksandar, Živković Milan, Živković Dušan, Popović Lidija, Veličković Zorana, Miladinović Milan, Šubarić Ljiljana, Marjanović Dragan, Cvetković Andrijana   +8 more
doaj   +1 more source

Case Report: A Novel COL1A1 Missense Mutation Associated With Dentineogenesis Imperfecta Type I

Frontiers in Genetics, 2021
Background: Osteogenesis imperfecta (OI) is a clinical and genetic disorder that results in bone fragility, blue sclerae and dentineogenesis imperfecta (DGI), which is mainly caused by a mutation in the COL1A1 or COL1A2 genes, which encode type I ...
Yuting Zeng, Yuhua Pan, Jiayao Mo, Zhiting Ling, Lifang Jiang, Fu Xiong, Fu Xiong, Wenjuan Yan   +7 more
doaj   +1 more source