Results 21 to 30 of about 9,324 (181)

circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046

Frontiers in Physiology, 2022
circular RNAs (circRNAs) is a broad and diverse endogenous subfamily of non-coding RNAs, regulating the gene expression by acting as a microRNA (miRNA) sponge.
Yue Zhang, Hao Zhang, Guohua Yuan, Guobin Yang   +3 more
doaj   +1 more source

Mechanical Stimulation-Induced Calcium Signaling by Piezo1 Channel Activation in Human Odontoblast Reduces Dentin Mineralization

Frontiers in Physiology, 2021
Odontoblasts play critical roles in dentin formation and sensory transduction following stimuli on the dentin surface. Exogenous stimuli to the dentin surface elicit dentinal sensitivity through the movement of fluids in dentinal tubules, resulting in ...
Mayumi Matsunaga, Mayumi Matsunaga, Maki Kimura, Takehito Ouchi, Takashi Nakamura, Sadao Ohyama, Masayuki Ando, Sachie Nomura, Toshifumi Azuma, Tatsuya Ichinohe, Yoshiyuki Shibukawa   +10 more
doaj   +1 more source

Pathological dentinogenesis in posteruptiv toot development [PDF]

Stomatološki glasnik Srbije, 2004
The most significant investigations concerning pathological dentinogenesis are reviewed in this article. Previous results point out that odontoblasts behave, either in physiological or pathological circumstances, in the genetically determined sequence of
Vojinović Jovan, Stevanović Radoje
doaj   +1 more source

Functional Expression of IP, 5-HT₄, D₁, A_2A, and VIP Receptors in Human Odontoblast Cell Line

Biomolecules, 2023
Odontoblasts are involved in sensory generation as sensory receptor cells and in dentin formation. We previously reported that an increase in intracellular cAMP levels by cannabinoid 1 receptor activation induces Ca2+ influx via transient receptor ...
Eri Kitayama, Maki Kimura, Takehito Ouchi, Masahiro Furusawa, Yoshiyuki Shibukawa   +4 more
doaj   +1 more source

Radiographic and histopathologic outcomes of immature dog teeth with apical periodontitis after revascularization using propolis. An in vivo study

Saudi Endodontic Journal, 2020
Introduction: This study aimed to assess the radiographic and histopathologic outcomes of immature dog teeth with apical periodontitis after revascularization using propolis.
Nelly Abdelsalam, Ashraf M Abu-Seida, Dalia Fayyad, Hossam Tawfik   +3 more
doaj   +1 more source

Gα_s-Coupled CGRP Receptor Signaling Axis from the Trigeminal Ganglion Neuron to Odontoblast Negatively Regulates Dentin Mineralization

Biomolecules, 2022
An inflammatory response following dental pulp injury and/or infection often leads to neurogenic inflammation via the axon reflex. However, the detailed mechanism underlying the occurrence of the axon reflex in the dental pulp remains unclear.
Natsuki Saito, Maki Kimura, Takehito Ouchi, Tatsuya Ichinohe, Yoshiyuki Shibukawa   +4 more
doaj   +1 more source

Transforming Growth Factor-β Signaling Regulates Tooth Root Dentinogenesis by Cooperation With Wnt Signaling

Frontiers in Cell and Developmental Biology, 2021
Proper differentiation of odontoblasts is crucial for the development of tooth roots. Previous studies have reported the osteogenic/odontogenic potential of pre-odontoblasts during root odontoblast differentiation.
Ran Zhang, Ran Zhang, Jingting Lin, Yang Liu, Shurong Yang, Qi He, Liang Zhu, Xiao Yang, Guan Yang   +8 more
doaj   +1 more source

Case Report: A Novel COL1A1 Missense Mutation Associated With Dentineogenesis Imperfecta Type I

Frontiers in Genetics, 2021
Background: Osteogenesis imperfecta (OI) is a clinical and genetic disorder that results in bone fragility, blue sclerae and dentineogenesis imperfecta (DGI), which is mainly caused by a mutation in the COL1A1 or COL1A2 genes, which encode type I ...
Yuting Zeng, Yuhua Pan, Jiayao Mo, Zhiting Ling, Lifang Jiang, Fu Xiong, Fu Xiong, Wenjuan Yan   +7 more
doaj   +1 more source

Cellular Dynamics and Dentine Bridge Formation Following Direct Pulp Capping With MTA and Biodentine in a Murine Model. [PDF]

Int Endod J
ABSTRACT Aim Formation of a mineralized dentine bridge is the hallmark of successful direct pulp capping (DPC). Mineral trioxide aggregate (MTA) and Biodentine are widely used capping materials, but in vivo evidence comparing their regenerative potential remains inconclusive. This study used a controlled murine model to compare dentine bridge formation
Sajdeya A, Milgram J, Kot-Limon N, Abramovitz I, Sharir A.   +4 more
europepmc   +2 more sources

Use of calcium hydroxyapatite and growth factors in endodontic therapy [PDF]

Vojnosanitetski Pregled, 2021
Background/Aim. Hydroxyapatite (HAp) is one of the most commonly used calcium phosphate bioceramics with osteoconductive properties. Growth factors are capable of directly inducing morphological and functional differentiation of neodontoblasts.
Mitić Aleksandar, Živković Milan, Živković Dušan, Popović Lidija, Veličković Zorana, Miladinović Milan, Šubarić Ljiljana, Marjanović Dragan, Cvetković Andrijana   +8 more
doaj   +1 more source