Results 11 to 20 of about 9,236 (227)

Functional expression of TRPM8 and TRPA1 channels in rat odontoblasts. [PDF]

PLoS ONE, 2013
Odontoblasts produce dentin during development, throughout life, and in response to pathological conditions by sensing stimulation of exposed dentin. The functional properties and localization patterns of transient receptor potential (TRP) melastatin ...
Maki Tsumura, Ubaidus Sobhan, Masaki Sato, Miyuki Shimada, Akihiro Nishiyama, Aya Kawaguchi, Manabu Soya, Hidetaka Kuroda, Masakazu Tazaki, Yoshiyuki Shibukawa   +9 more
doaj   +2 more sources

Potassium Currents Activated by Depolarization in Odontoblasts

Frontiers in Physiology, 2017
Increased intracellular free Ca2+ concentrations elicit plasma membrane depolarization, which leads to the activation of K+ currents. However, the precise properties of K+ currents activated by depolarization in odontoblasts remain to be elucidated.
Yuki Kojima, Maki Kimura, Asuka Higashikawa, Kyosuke Kono, Masayuki Ando, Masakzu Tazaki, Yoshiyuki Shibukawa   +6 more
doaj   +2 more sources

Potential role of odontoblasts in the innate immune response of the dental pulp [PDF]

Dental Journal, 2008
Background: Odontoblasts are the cells lining of tooth’s hard structure at the dentin-pulp border, which become the first cells encountered oral microorganisms entering dentin.
Tetiana Haniastuti
doaj   +3 more sources

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]

Cell Prolif
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Zeng W, Lin Y, Gao Y, Huang D, Li Y, Ruan H, Yuan G, Liu H, Chen Z.   +8 more
europepmc   +2 more sources

Topical review. Dental pain and odontoblasts: facts and hypotheses.

, 2010
International audienceDental pain arises from exposed dentin following bacterial, chemical, or mechanical erosion of enamel and/or recession of gingiva.
Magloire, Henry, Shibukawa, Yoshiyuki, Maurin, Jean Christophe, Couble, Marie Lise, Bleicher, Francoise, Thivichon-Prince, Beatrice, Tsumura, Maki   +6 more
core   +6 more sources

Modeling the Histogenetic Switch Between Enameloid and Enamel. [PDF]

Evol Dev
This evo–devo exploration of ~550,000 histogenetic simulations forming dentine, enameloid, and enamel identifies 38 independent ways to induce the enameloid–enamel transition, with delayed matrix vesicle secretion (SVO‐) emerging as the key modification, providing new insights into the origin of enamel in early osteichthyans.
Houée G, Bardin J, Germain D, Goudemand N.   +3 more
europepmc   +2 more sources

Radiographic and histopathologic outcomes of immature dog teeth with apical periodontitis after revascularization using propolis. An in vivo study

Saudi Endodontic Journal, 2020
Introduction: This study aimed to assess the radiographic and histopathologic outcomes of immature dog teeth with apical periodontitis after revascularization using propolis.
Nelly Abdelsalam, Ashraf M Abu-Seida, Dalia Fayyad, Hossam Tawfik   +3 more
doaj   +1 more source

Functional Expression of IP, 5-HT₄, D₁, A_2A, and VIP Receptors in Human Odontoblast Cell Line

Biomolecules, 2023
Odontoblasts are involved in sensory generation as sensory receptor cells and in dentin formation. We previously reported that an increase in intracellular cAMP levels by cannabinoid 1 receptor activation induces Ca2+ influx via transient receptor ...
Eri Kitayama, Maki Kimura, Takehito Ouchi, Masahiro Furusawa, Yoshiyuki Shibukawa   +4 more
doaj   +1 more source

Transforming Growth Factor-β Signaling Regulates Tooth Root Dentinogenesis by Cooperation With Wnt Signaling

Frontiers in Cell and Developmental Biology, 2021
Proper differentiation of odontoblasts is crucial for the development of tooth roots. Previous studies have reported the osteogenic/odontogenic potential of pre-odontoblasts during root odontoblast differentiation.
Ran Zhang, Ran Zhang, Jingting Lin, Yang Liu, Shurong Yang, Qi He, Liang Zhu, Xiao Yang, Guan Yang   +8 more
doaj   +1 more source

Use of calcium hydroxyapatite and growth factors in endodontic therapy [PDF]

Vojnosanitetski Pregled, 2021
Background/Aim. Hydroxyapatite (HAp) is one of the most commonly used calcium phosphate bioceramics with osteoconductive properties. Growth factors are capable of directly inducing morphological and functional differentiation of neodontoblasts.
Mitić Aleksandar, Živković Milan, Živković Dušan, Popović Lidija, Veličković Zorana, Miladinović Milan, Šubarić Ljiljana, Marjanović Dragan, Cvetković Andrijana   +8 more
doaj   +1 more source