The FASEB Journal, Volume 39, Issue 14, 31 July 2025.Aged amelogenin‐null mice developed severe osteoarthritic features. In a rat model of induced osteoarthritis, a single application of a recombinant human amelogenin inhibited joint deterioration and induced partial healing, while increasing type II collagen and decreasing MMP‐13 and type X collagen, 24 weeks posttreatment.
Omer Helwa‐Shalom +12 more
wiley +1 more source
Les phosphoprotéines sécrétées liant le calcium (SCPP) impliquées dans la formation de l'émail dentaire : expression chez le lézard Anolis carolinensis et évolution chez les amniotes [PDF]
, 2015 Enamel formation requires the involvement of secretory calcium-binding phosphoproteins. Three of them, amelogenin (AMEL), ameloblastin (AMBN) and enamelin (ENAM), have been extensively studied in mammals.
Gasse, Barbara
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A prospective clinical study of polycarboxylate cement in periapical surgery [PDF]
, 2011 Objective: To evaluate the clinical efficacy of polycarboxylate cement as retrograde filling material. Design: A prospective clinical study was made of 25 patients subjected to periapical surgery with ultrasound and magnifying loupes, in which ...
García Mira, Berta +5 more
core +1 more source
Co-distribution of cysteine cathepsins and matrix metalloproteases in human dentin [PDF]
, 2017 It has been hypothesized that cysteine cathepsin's (CTs) along with matrix metalloproteases (MMPs) may work in conjunction in the proteolysis of mature dentin matrix.
Apolonio, Fabianni +11 more
core +2 more sources
Mechanisms of Development, 2004 Parathyroid hormone (PTH)-related protein (PTH-rP) is an important autocrine/paracrine attenuator of programmed cell differentiation whose expression is restricted to the epithelial layer in tooth development. The PTH/PTHrP receptor (PPR) mRNA in contrast is detected in the dental papilla, suggesting that PTHrP and the PPR may modulate epithelial ...
M.F. Young +6 more
openaire +3 more sources
The Bio-Molecular Dynamics of Dental Pulp in Different Clinical Scenarios [PDF]
, 2015 Dental pulp (DP) is a very dynamic tissue both in health and in disease. When exposed to stressors and pathological conditions. It undergoes a complex series of biological reactions whereby alterations affect the pulp tissue at tissue cellular and ...
BONAVENTURA, Giuseppe +3 more
core
Role of Prion protein-EGFR multimolecular complex during neuronal differentiation of human dental pulp-derived stem cells [PDF]
, 2018 Cellular prion protein (PrPC) is expressed in a wide variety of stem cells in which regulates their self-renewal as well as differentiation potential. In this study we investigated the presence of PrPCin human dental pulp-derived stem cells (hDPSCs) and ...
Manganelli, Valeria +6 more
core +1 more source
The Isolation and Examination of Odontoblasts in the Fresh Unfixed State [PDF]
, 1956 Ivor R. H. Kramer
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Observations on pulpal response to carbon dioxide laser drilling of dentine in healthy human third molars [PDF]
, 2018 Preservation of pulpal health is the primary prerequisite for successful application of laser systems in the hard tissue management of vital teeth. The purpose of this study was to investigate the short and long-term pulpal effects to cavity preparations
Baltensperger, M. +3 more
core
Ultrastructural localization of alkaline phosphatases in rat incisor odontoblasts. [PDF]
, 1978 Gösta Granström +2 more
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