Results 21 to 30 of about 12,751 (221)

High pH-Sensitive Store-Operated Ca2+ Entry Mediated by Ca2+ Release-Activated Ca2+ Channels in Rat Odontoblasts

Frontiers in Physiology, 2018
Odontoblasts play a crucial role in dentin formation and sensory transduction following the application of stimuli to the dentin surface. Various exogenous and endogenous stimuli elicit an increase in the intracellular free calcium concentration ([Ca2+]i)
Maki Kimura, Koichi Nishi, Asuka Higashikawa, Sadao Ohyama, Sadao Ohyama, Kaoru Sakurai, Masakazu Tazaki, Yoshiyuki Shibukawa   +7 more
doaj   +1 more source

Dentin defects caused by a Dspp −1 frameshift mutation are associated with the activation of autophagy

Scientific Reports, 2023
Dentin sialophosphoprotein (DSPP) is primarily expressed by differentiated odontoblasts (dentin-forming cells), and transiently expressed by presecretory ameloblasts (enamel-forming cells).
Tian Liang, Charles E. Smith, Yuanyuan Hu, Hong Zhang, Chuhua Zhang, Qian Xu, Yongbo Lu, Ling Qi, Jan C.-C. Hu, James P. Simmer   +9 more
doaj   +1 more source

Influence of Hydrogen Peroxide on Mineralization in Dental Pulp Cells: A Systematic Review

Frontiers in Dental Medicine, 2021
Background: Dental bleaching agents show the ability to permeate through dental hard tissues, which may lead to pulp tissue changes. This systematic review (PROSPERO register: CRD42020213767) is aimed at understanding the effects of bleaching agents on ...
Alexandre Henrique dos Reis-Prado, Isadora Rodrigues Grossi, Hebertt Gonzaga dos Santos Chaves, Carolina Bosso André, Luís Fernando dos Santos Alves Morgan, André Luiz Fraga Briso, Luciano Tavares Angelo Cintra, Francine Benetti   +7 more
doaj   +1 more source

Hypoxia in the Initiation and Progression of Neuroblastoma Tumours [PDF]

, 2020
Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to ...
Gómez Muñoz, María Ángeles, Huertas Castaño, Carlos, Pardal Redondo, Ricardo, Vega Moreno, Francisco Manuel   +3 more
core   +1 more source

Intercellular odontoblast communication via ATP mediated by pannexin-1 channel and phospholipase C-coupled receptor activation.

Frontiers in Physiology, 2015
Extracellular ATP released via pannexin-1 channels, in response to the activation of mechanosensitive-TRP channels during odontoblast mechanical stimulation, mediates intercellular communication among odontoblasts in dental pulp slice preparation ...
Masaki eSato, Tadashi eFuruya, Tadashi eFuruya, Maki eKimura, Yuki eKojima, Masakazu eTazaki, Toru eSato, Yoshiyuki eShibukawa   +7 more
doaj   +1 more source

Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression [PDF]

, 2010
Background: The development of teeth is the result of interactions between competent mesenchyme and epithelium, both of which undergo extensive morphogenesis.
Verstraeten, Barbara, Sanders, Ellen, van Hengel, Jolanda, Huysseune, Ann   +3 more
core   +2 more sources

Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]

, 2011
Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey, Asrari, Barthel, Bègue-Kirn, Cabrera, Camargo, Doug Lobner, Duailibi, D’Souza, Fogal, Franco, Furey, Goldberg, Gronthos, Hansen, Hu, Kalyva, Katherine Pauly, Kaur, Keelan, Kim, Kim, Kymberly Fritz, Lobner, Lovschall, Marcato, Nie, Onishi, Pacheco, Paranjpe, Piani, Piattelli, Ricketts, Rutherford, Stanley, Stockton, Tziafas, Tziafas, Ward, Wood   +39 more
core   +2 more sources

Evaluation of nano-hydroxyapatite application on fluorosed and nonfluorosed dentinal surface: A scanning electron microscope study

Saudi Journal of Oral Sciences, 2023
Introduction: Although there are many desensitizing medications on the market with promising results, their therapeutic advantages are sometimes fleeting or diminished over time since they might be gradually destroyed by consistent tooth brushing or ...
Kharidhi Laxman Vandana, Vangara Aditya, Neha Mahajan   +2 more
doaj   +1 more source

Physiologic dentin regeneration: its past, present, and future perspectives

Frontiers in Physiology, 2023
Regenerative dentistry has rapidly progressed since the advancement of stem cell biology and material science. However, more emphasis has been placed on the success of tissue formation than on how well the newly generated tissue retains the original ...
Myungjin Lee, Yoon Seon Lee, Won-Jun Shon, Joo-Cheol Park   +3 more
doaj   +1 more source

Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer [PDF]

, 2019
Background. Fibronectin type III domain-containing (FNDC) proteins fulfill manifold functions in tissue development and regulation of cellular metabolism.
Adler, Andreas, Aigner, Felix, Becker, Olaf, Biebl, Matthias, Bosma, Madeleen, Pratschke, Johann, Quint, Janina, Spitz, Wolfgang, Stockmann, Martin, Veltzke-Schlieker, Wilfried, Weiss, Sascha, Wizenty, Jonas, Wuensch, Tilo   +12 more
core   +2 more sources