Results 21 to 30 of about 14,320 (271)

Case Report: A Novel COL1A1 Missense Mutation Associated With Dentineogenesis Imperfecta Type I

Frontiers in Genetics, 2021
Background: Osteogenesis imperfecta (OI) is a clinical and genetic disorder that results in bone fragility, blue sclerae and dentineogenesis imperfecta (DGI), which is mainly caused by a mutation in the COL1A1 or COL1A2 genes, which encode type I ...
Yuting Zeng, Yuhua Pan, Jiayao Mo, Zhiting Ling, Lifang Jiang, Fu Xiong, Fu Xiong, Wenjuan Yan   +7 more
doaj   +1 more source

Microbiological Aspects and Immunity Response of Bacteria Causing Pulpitis [PDF]

, 2011
The oral cavity is a very widely distributed ecosystem in which several hundred microbial species normally cohabit harmoniously. Under special conditions some microorganisms with potential are promoted, leading to inflammation & infection by ...
Deepak Dwivedi, Dr. Vinod Singh, Sapna Kushwah   +2 more
core   +2 more sources

Hypoxia in the Initiation and Progression of Neuroblastoma Tumours [PDF]

, 2020
Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to ...
Gómez Muñoz, María Ángeles, Huertas Castaño, Carlos, Pardal Redondo, Ricardo, Vega Moreno, Francisco Manuel   +3 more
core   +1 more source

An Innovative "Tooth-On-Chip" Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue. [PDF]

Adv Healthc Mater
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Cordiale A, Stanco D, Visone R, Stadlinger B, Pagella P, Rasponi M, Mitsiadis TA.   +6 more
europepmc   +2 more sources

Meeting report: a hard look at the state of enamel research. [PDF]

, 2017
The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D, DenBesten, Pamela, Diekwisch, Thomas Gh, Duverger, Olivier, Joester, Derk, Klein, Ophir D, Kulkarni, Ashok B, Lacruz, Rodrigo S, Millar, Sarah E, Moradian-Oldak, Janet, Pugach, Megan K, Shaw, Wendy, Simmer, James P, Wright, J Timothy   +13 more
core   +1 more source

High pH-Sensitive Store-Operated Ca2+ Entry Mediated by Ca2+ Release-Activated Ca2+ Channels in Rat Odontoblasts

Frontiers in Physiology, 2018
Odontoblasts play a crucial role in dentin formation and sensory transduction following the application of stimuli to the dentin surface. Various exogenous and endogenous stimuli elicit an increase in the intracellular free calcium concentration ([Ca2+]i)
Maki Kimura, Koichi Nishi, Asuka Higashikawa, Sadao Ohyama, Sadao Ohyama, Kaoru Sakurai, Masakazu Tazaki, Yoshiyuki Shibukawa   +7 more
doaj   +1 more source

Dentin defects caused by a Dspp −1 frameshift mutation are associated with the activation of autophagy

Scientific Reports, 2023
Dentin sialophosphoprotein (DSPP) is primarily expressed by differentiated odontoblasts (dentin-forming cells), and transiently expressed by presecretory ameloblasts (enamel-forming cells).
Tian Liang, Charles E. Smith, Yuanyuan Hu, Hong Zhang, Chuhua Zhang, Qian Xu, Yongbo Lu, Ling Qi, Jan C.-C. Hu, James P. Simmer   +9 more
doaj   +1 more source

Influence of Hydrogen Peroxide on Mineralization in Dental Pulp Cells: A Systematic Review

Frontiers in Dental Medicine, 2021
Background: Dental bleaching agents show the ability to permeate through dental hard tissues, which may lead to pulp tissue changes. This systematic review (PROSPERO register: CRD42020213767) is aimed at understanding the effects of bleaching agents on ...
Alexandre Henrique dos Reis-Prado, Isadora Rodrigues Grossi, Hebertt Gonzaga dos Santos Chaves, Carolina Bosso André, Luís Fernando dos Santos Alves Morgan, André Luiz Fraga Briso, Luciano Tavares Angelo Cintra, Francine Benetti   +7 more
doaj   +1 more source

Intercellular odontoblast communication via ATP mediated by pannexin-1 channel and phospholipase C-coupled receptor activation.

Frontiers in Physiology, 2015
Extracellular ATP released via pannexin-1 channels, in response to the activation of mechanosensitive-TRP channels during odontoblast mechanical stimulation, mediates intercellular communication among odontoblasts in dental pulp slice preparation ...
Masaki eSato, Tadashi eFuruya, Tadashi eFuruya, Maki eKimura, Yuki eKojima, Masakazu eTazaki, Toru eSato, Yoshiyuki eShibukawa   +7 more
doaj   +1 more source

Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression [PDF]

, 2010
Background: The development of teeth is the result of interactions between competent mesenchyme and epithelium, both of which undergo extensive morphogenesis.
Huysseune, Ann, Sanders, Ellen, van Hengel, Jolanda, Verstraeten, Barbara   +3 more
core   +3 more sources