ABSTRACT Head and neck radiotherapy (HNRT) can expose teeth to moderate radiation doses, yet the effects on root dentine under clinically relevant conditions remain unclear. This in vitro study compared dentine subjected to 0, 30, or 50 Gy IMRT. Palatal roots from 35 maxillary molars were allocated to non‐irradiated, 30 Gy (oropharyngeal simulation ...
Anna Victória Costa Serique +11 more
wiley +1 more source
Crosstalk between nuclear factor I-C and transforming growth factor-β1 signaling regulates odontoblast differentiation and homeostasis. [PDF]
Transforming growth factor-β1 (TGF-β1) signaling plays a key role in vertebrate development, homeostasis, and disease. Nuclear factor I-C (NFI-C) has been implicated in TGF-β1 signaling, extracellular matrix gene transcription, and tooth root development.
Dong-Seol Lee +6 more
doaj +1 more source
Enamel proteins and proteases in Mmp20 and Klk4 null and double‐null mice [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90347/1/j.1600-0722.2011.00866.x ...
Bartlett +55 more
core +1 more source
Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang +9 more
wiley +1 more source
Intra-pulp temperature increase of equine cheek teeth during treatment with motorized grinding systems : influence of grinding head position and rotational speed [PDF]
BACKGROUND: In equine practice, teeth corrections by means of motorized grinding systems are standard procedure. The heat resulting from that treatment may cause irreparable damage to the dental pulp. It has been shown that a 5.5degreesC temperature rise
Haeussler, Silvia +3 more
core +2 more sources
p75NTR Promotes Circadian‐Driven Mineralization During Tooth Development via CK2/PER2 Pathway
The diagram illustrates how the circadian rhythm regulates the p75NTR‐CK2‐PER2 axis, driving rhythmic biomineralisation during tooth development. ABSTRACT Circadian rhythm is an essential biological process that synchronises physiological activities with environmental light/dark cycles.
Manzhu Zhao +8 more
wiley +1 more source
Review of: "Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9" [PDF]
Hiroaki Nakamura
openalex +1 more source
37% Phosphoric Acid Induced Stronger Matrix Metalloproteinase-8 Expression of the Dental Pulp Than 19% Ethylene Diamine Tetraacetic Acid [PDF]
Etching agents such as ethylene diamine tetraacetic acid (EDTA) and phosphoric acid which are widely used in adhesive restoration system aimed to increase for retention of restorative materials, may act a chemical irritant that induce inflammation of ...
Fatimatuzzahro, N. (Nadie) +2 more
core +2 more sources
Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk +2 more
wiley +1 more source
Synthetic oligodeoxynucleotides (ODNs) containing unmethylated cytosine–phosphate–guanine (CpG) motifs (CpG-ODNs) are ligand molecules for Toll-like receptor 9 (TLR9), which is expressed by odontoblasts in vitro and dental pulp cells.
Angela Quispe-Salcedo +2 more
doaj +1 more source

