Results 21 to 30 of about 10,398 (278)

Small RNAs and tooth development: The role of microRNAs in tooth agenesis and impaction [PDF]

Journal of Dental Sciences
Background/purpose: Tooth development, or odontogenesis, is a complex process in which several molecular pathways play a key role. Recently, microRNAs, a class of approximately 20-nucleotide small RNA molecules that regulate gene expression, have been ...
Agnese Giovannetti, Rosanna Guarnieri, Francesco Petrizzelli, Sara Lazzari, Gabriella Padalino, Alice Traversa, Alessandro Napoli, Roberto Di Giorgio, Antonio Pizzuti, Chiara Parisi, Tommaso Mazza, Ersilia Barbato, Viviana Caputo   +12 more
doaj   +2 more sources

Cathepsin K‐Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog [PDF]

Advanced Science
Oral diseases affect nearly half of the global population throughout their lifetime causing pain, as estimated by the World Health Organization. Preservation of vital pulp is the therapeutic core as well as a challenge to protect natural teeth.
Ruoshi Xu, Xiaohan Zhang, Weimin Lin, Yushun Wang, Danting Zhang, Shuang Jiang, Linfeng Liu, Jiaying Wang, Xutao Luo, Xiao Zhang, Junjun Jing, Quan Yuan, Chenchen Zhou   +12 more
doaj   +2 more sources

Molecular insight into odontogenesis in hyperglycemic environment: A systematic review

Journal of Pharmacy and Bioallied Sciences, 2020
Diabetes mellitus is an endocrinal disorder affecting worldwide and the disease incidence is rising alarmingly high. The effects of diabetes on tooth development are explored by limited studies and their molecular insights are very rarely studied.
Andamuthu Yamunadevi, Ramani Pratibha, Muthusamy Rajmohan, Nalliappan Ganapathy, Jeyachandran Porkodisudha, Dhanasing Pavithrah, Sengottaiyan Mahendraperumal   +6 more
doaj   +2 more sources

The metamorphic transition of the frog mouth: from tadpole keratinized mouthparts to adult teeth [PDF]

Royal Society Open Science
Teeth have been a prominent feature of most vertebrates for 400 million years, and the core regulatory network underlying embryonic tooth formation is deeply conserved.
Daniel J. Paluh, Madeline Brinkman, Kyliah Gilliam-Beale, Daniela Salcedo-Recio, Jacob Szafranski, James Hanken, Gareth J. Fraser   +6 more
doaj   +2 more sources

Sonic Hedgehog Signaling and Development of the Dentition [PDF]

Journal of Developmental Biology, 2017
Sonic hedgehog (Shh) is an essential signaling peptide required for normal embryonic development. It represents a highly-conserved marker of odontogenesis amongst the toothed vertebrates.
Maisa Seppala, Gareth J. Fraser, Anahid A. Birjandi, Guilherme M. Xavier, Martyn T. Cobourne   +4 more
doaj   +3 more sources

The Essential Role of Proteoglycans and Glycosaminoglycans in Odontogenesis

Journal of Dental Research
Tooth development and regeneration are regulated through a complex signaling network. Previous studies have focused on the exploration of intracellular signaling regulatory networks, but the regulatory roles of extracellular networks have only been revealed recently.
J. Chen, T. Sun, B. Lin, B. Wu, J. Wu
openaire   +3 more sources

Mesoporous Bioactive Glass Nanoparticles Promote Odontogenesis and Neutralize Pathophysiological Acidic pH

Frontiers in Materials, 2020
Pathophysiological acidic-pH hinders the dental biomaterial-based pulp-dentin regeneration. Bioactive glass (BG) synthesized by sol-gel methods had shown odontogenic and pulp regeneration potential.
Wenyan Huang, Jingjing Yang, Qiong Feng, Yan Shu, Yan Shu, Cong Liu, Shihan Zeng, Hongbing Guan, Lihong Ge, Lihong Ge, Janak L. Pathak, Sujuan Zeng   +11 more
doaj   +2 more sources

Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1 [PDF]

Scientific Reports, 2019
Signal transmission from the mechanical forces to the various intracellular activities is a fundamental process during tissue development. Despite their critical role, the mechanism of mechanical forces in the biological process is poorly understood.
Aya Miyazaki, Asuna Sugimoto, Keigo Yoshizaki, Keita Kawarabayashi, Kokoro Iwata, Rika Kurogoushi, Takamasa Kitamura, Kunihiro Otsuka, Tomokazu Hasegawa, Yuki Akazawa, Satoshi Fukumoto, Naozumi Ishimaru, Tsutomu Iwamoto   +12 more
openalex   +2 more sources

Polydopamine-coated bioactive glass for immunomodulation and odontogenesis in pulpitis

Materials Today Bio
Jingyi Li, Jilin Wu, Lin Zhu, Sicong Mao, Sainan Wang, Peipei Jia, Yanmei Dong   +6 more
openalex   +2 more sources

Odontogenesis-associated phosphoprotein (ODAPH) Promotes Ameloblast adhesion and alkaline phosphatase (ALP) expression via LAMC2/ ITGB6/TGF-β1 signaling pathway. [PDF]

PLoS One
Li M, Zhang J, Xiao S, Liu X, Song S, Ye X, Bi R, Gao Y, Zhang L.   +8 more
europepmc   +2 more sources