Results 111 to 120 of about 22,691 (229)

Functional evolution of mammalian odorant receptors.

open access: yesPLoS Genetics, 2012
The mammalian odorant receptor (OR) repertoire is an attractive model to study evolution, because ORs have been subjected to rapid evolution between species, presumably caused by changes of the olfactory system to adapt to the environment.
Kaylin A Adipietro   +2 more
doaj   +1 more source

A carboxylesterase, Esterase-6, modulates sensory physiological and behavioral response dynamics to pheromone in Drosophila [PDF]

open access: yes, 2012
Conclusions: Our study presents evidence that Est-6 plays a role in the physiological and behavioral dynamics of sex pheromone response in Drosophila males and supports a role of Est-6 as an odorant-degrading enzyme (ODE) in male antennae.
Chertemps, Thomas   +6 more
core  

Transition Metal‐Catalyzed Functionalization of Nonallylic Alkenyl Alcohols via Chain‐Walking Strategies

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
This minireview outlines recent advances in chain‐walking reactions of nonallylic alkenyl alcohols catalyzed by various transition metals, including palladium, ruthenium, rhodium, iridium, and nickel. Furthermore, the corresponding reaction mechanisms are discussed.
Yong Huang   +5 more
wiley   +1 more source

Evaluation of the DREAM Technique for a High-Throughput Deorphanization of Chemosensory Receptors in Drosophila

open access: yesFrontiers in Molecular Neuroscience, 2018
In the vinegar fly Drosophila melanogaster, the majority of olfactory receptors mediating the detection of volatile chemicals found in their natural habitat have been functionally characterized (deorphanized) in vivo. In this process, receptors have been
Sarah Koerte   +6 more
doaj   +1 more source

Early and Sustained Improvements in Sense of Smell With Tezepelumab Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyps (WAYPOINT)

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 5, Page 484-494, May 2026.
ABSTRACT Background Loss of smell is a principal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), affecting health‐related quality of life and posing a safety hazard. Methods WAYPOINT (NCT04851964), a phase 3, multicenter trial in adults with uncontrolled CRSwNP, randomized patients 1:1 to receive tezepelumab 210 mg or placebo ...
Joaquim Mullol   +14 more
wiley   +1 more source

Antennal and abdominal transcriptomes reveal chemosensory gene families in the coconut hispine beetle, Brontispa longissima

open access: yesScientific Reports, 2017
Antennal and abdominal transcriptomes of males and females of the coconut hispine beetle Brontispa longissima were sequenced to identify and compare the expression patterns of genes involved in odorant reception and detection.
Shu-Ying Bin   +5 more
doaj   +1 more source

The Olfactory Nervous System Of Terrestrial And Aquatic Vertebrates [PDF]

open access: yes, 2011
Animals in their natural milieu are surrounded by odors. These odors are rich source of information, and are perceived by sophisticated olfactory systems, that have evolved over time.
Ashiq Hussain
core   +1 more source

Comparative Analysis Reveals the Adaptive Evolution of Olfactory System in the Swamp Eel (Monopterus albus) Based on the Chromosome‐Level Genome

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
A total of 629 gene families were identified to expand in the swamp eel, with five (OLFR, GNAL, PRKG1, NCALD, and PDE1) distributed in olfactory transduction (KEGG map04740). A total of 318 OR genes (289 functional genes, 10 partial genes, and 19 pseudogenes) were annotated in the swamp eel genome, significantly surpassing other fish species.
Chuang Zhou   +3 more
wiley   +1 more source

Testing odorant-receptor interaction theories in humans through discrimination of isotopomers

open access: yesJournal of Biological Research, 2017
Odour reception takes place on the olfactory receptor neuron membrane, where molecular receptors interact with volatile odorant molecules. This interaction is classically thought to rely on chemical and structural features of the odorant, e.g.
Mara Andrione   +3 more
doaj   +1 more source

Machine Learning Approaches for GC–MS Data Interpretation in Flavour and Fragrance Analysis

open access: yesFlavour and Fragrance Journal, Volume 41, Issue 3, Page 437-448, May 2026.
The review explores machine learning integration in GC‐MS data analysis for the fragrance and flavour industry, highlighting recent advances and techniques in a context constrained by data scarcity and intellectual property concerns. ABSTRACT This review explores the integration of machine learning (ML) in the analysis of mass spectrometry data ...
Jean‐Baptiste Coffin   +3 more
wiley   +1 more source

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