Results 31 to 40 of about 4,324,109 (221)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Offset-free Model Predictive Control for Non-linear Uncertain Systems

open access: yes
This work focuses on the robust tracking problem of non-linear systems subject to parametric uncertainties and external disturbances. We present two controller design approaches: a non-linear offset-free model predictive control approach and a robust ...
Haoran Zhang (731854)
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Offset-free nonlinear MPC for systems learned by LSTM networks [PDF]

open access: yes, 2021
LAUREA MAGISTRALEIn molte applicazioni recenti, le reti LSTM (Long Short Term Memory) sono state impiegate con successo per l’analisi e la previsione di serie temporali.
Oliveira da Silva, Caio Fábio
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A Non-Linear Offset-Free Model Predictive Control Design Approach

open access: yes
This paper presents a non-linear model predictive control approach for offset-free tracking and the rejection of piece-wise constant disturbances.
Emmanuel Prempain (17000532)   +1 more
core   +7 more sources

Blind Multi-User Equalisation for a Dispersive DS-CDMA Downlink under Carrier Frequency Offset Conditions

open access: yes, 2004
We address blind multiuser detection in a DS-CDMA downlink channel in the presence of carrier frequency offset. The synchronous users are separated by re-establishing orthogonality of their spreading sequences in a shared equaliser at the chip level. The
Weiss, S   +5 more
core   +1 more source

Utilizing large hall offset voltage for conversion free 4H-SiC strain sensor

open access: yes, 2018
This work presents a conversion free p-type 4H silicon carbide (4H-SiC) four-terminal strain sensor utilizing a large Hall offset voltage in a symmetric four-terminal configuration.
Nguyen, Nam-Trung   +20 more
core   +1 more source

Home - About - Disclaimer - Privacy