Results 41 to 50 of about 27,515 (197)

Linked open government data: lessons from Data.gov.uk [PDF]

, 2012
The movement to publish government data is an opportunity to populate the linked data Web with data of good provenance. The benefits range from transparency to public service improvement, citizen engagement to the creation of social and economic value ...
Berners-Lee, Tim, Gibbins, Nicholas, Glaser, Hugh, Hall, Wendy, O'Hara, Kieron, schraefel, m.c., Shadbolt, Nigel   +6 more
core   +1 more source

OGD Heartbeat: Cities’ Commitment to Open Data

JeDEM - eJournal of eDemocracy and Open Government, 2015
This paper develops and tests a theoretical model, which proposes to examine cities’ commitment to the concept of open government data (OGD) according to three typical levels. Level 1, Way of Life, indicates high commitment to OGD; Level 2, On the Fence, represents either a low or erratic commitment; Level 3, Lip Service, refers to either scarce or no ...
Karin Nahon, Alon Peled, Jenniver Shkabatur   +2 more
openaire   +2 more sources

Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation [PDF]

, 2009
CsA (cyclosporin A) is a hydrophobic undecapeptide that inhibits CyPs (cyclophilins), a family of PPIases (peptidylprolyl cis–trans isomerases). In some experimental models, CsA offers partial protection against lethal cell injury brought about by ...
Abramov, Asin-Cayuela, Baines, Basso, Baumgrass, Bonde, Brustovetsky, Capano, Crompton, Crompton, Crompton, Crompton, Crompton, David Selwood, Doyle, Duchen, Gillick, Griffiths, Haworth, Henderson, Henry Dube, Ishii, Javadov, Jin, Johnson, Kajitani, Kim, Kim, Kofron, Kokoszka, Leung, Li, Martin Crompton, McGuinness, Morioka, Murphy, Nazareth, Norris, Piot, Reynolds, Ruiz, Rytter, Schinzel, Seebach, Sylvanie Malouitre, Taylor, Uchino, Waldmeier, Yang, Zhu   +49 more
core   +3 more sources

Metadata quality matters in Open Government Data (OGD) evaluation! An empirical investigation of OGD portals of the GCC constituents:An empirical investigation of OGD portals of the GCC constituents [PDF]

, 2023
Purpose: The study seeks to investigate the quality of metadata associated with the open government data (OGD) portals of the six Gulf Cooperation Council (GCC) constituents – Bahrain (BH), Kuwait (KW), Oman (OM), Qatar (QA), Kingdom of Saudi Arabia (KSA) and United Arab Emirates (UAE).
Chokki, Abiola Paterne; id_orcid 0000-0003-4500-2141, Alexopoulos, Charalampos, Saxena, Stuti, Frénay, Benoît; id_orcid 0000-0002-7859-2750, Vanderose, Benoit; id_orcid 0000-0001-9752-0085, Ali, Mohsan   +5 more
openaire  

Open Government Data Use in the Brazilian States and Federal District Public Administrations

Data, 2022
This research investigates whether, why, and how open government data (OGD) is used and reused by Brazilian state and district public administrations. A new online questionnaire was developed and collected data from 26 of the 27 federation units between ...
Ilka Kawashita, Ana Alice Baptista, Delfina Soares   +2 more
doaj   +1 more source

OGD jako źródło danych w aplikacjach mobilnych

Dydaktyka Informatyki, 2021
OGD are crucial in terms of economic and business value, as well as achieving participatory democracy and civil society. It is enough to provide data sets collected and processed by the public administration in formats enabling their further application to trigger citizen’s creativity on how to exploit them usefully. These sets should be made available
openaire   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Prolonged astrocyte-derived erythropoietin expression attenuates neuronal damage under hypothermic conditions

Journal of Neuroinflammation, 2020
Background Hypoxic-ischemic encephalopathy (HIE) has a high morbidity rate and involves severe neurologic deficits, including cerebral palsy. Therapeutic hypothermia (TH) has been shown to decrease the mortality rate and provide neuroprotection in ...
Kohki Toriuchi, Hiroki Kakita, Tetsuya Tamura, Satoru Takeshita, Yasumasa Yamada, Mineyoshi Aoyama   +5 more
doaj   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source