Results 51 to 60 of about 14,327 (215)

Open government data portals in the European Union: A dataset from 2015 to 2017

open access: yesData in Brief, 2020
Open government data (OGD) portals are official websites where governments can publish OGD in a controlled way. OGD portals foster discoverability, accountability, and reusability for stakeholders.
Susana de Juana-Espinosa   +1 more
doaj   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

open access: yesAnnals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian   +9 more
wiley   +1 more source

Contribution of caspase-mediated apoptosis to the cell death caused by oxygen–glucose deprivation in cortical cell cultures

open access: yesNeurobiology of Disease, 2005
Several evidences suggest that cell death after cerebral ischemia involves both necrosis and apoptosis. However, it is still unknown which is the relative contribution of both types of cell death.
Cristina Malagelada   +4 more
doaj   +1 more source

Role of NKCC1 and KCC2 during hypoxia-induced neuronal swelling in the neonatal neocortex

open access: yesNeurobiology of Disease, 2023
Neonatal hypoxia causes cytotoxic neuronal swelling by the entry of ions and water. Multiple water pathways have been implicated in neurons because these cells lack water channels, and their membrane has a low water permeability.
Yusuke Takezawa   +5 more
doaj   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

open access: yesBMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong   +11 more
wiley   +1 more source

The Study of the Protection Mechanism of Calycosin-7-O-β-d-Glucoside Against Oxygen–Glucose Deprivation/Reperfusion in HT22 Cells Based on Non-Targeted Metabolomics and Network Analysis

open access: yesMolecules
The cell non-targeted metabolomics technique was used to investigate the potential mechanism of Caly-cosin-7-O-β-d-glucoside (CAG) against cell oxygen–glucose deprivation/reperfusion (OGD/R). The OGD/R-injured HT22 cell model was constructed.
Die Pei   +6 more
doaj   +1 more source

Online Gambling Disorder Questionnaire (OGD-Q): An item r‘esponse theory examination

open access: yesAddictive Behaviors Reports, 2022
Gambling disorder behaviours, such as one's preoccupation with gambling and/or mood modification due to gambling, have been proposed to differ in their diagnostic weight/importance, especially when informing diagnostic scales. Such potential differences are imperative to be considered to improve assessment accuracy. The latter is particularly important
V. Stavropoulos   +4 more
openaire   +5 more sources

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Butorphanol protects PC12 cells against OGD/R-induced inflammation and apoptosis

open access: yesMolecular Medicine Reports, 2020
The aim of the present study was to examine the effects of butorphanol on neural injury in an oxygen glucose deprivation/reoxygenation (OGD/R) model using PC12 cells, and to investigate whether mitochondrial apoptosis was involved in these effects.
Yang, Zijing   +3 more
openaire   +3 more sources

Diterpenoid Diversity across Land Plants

open access: yesHelvetica Chimica Acta, EarlyView.
Here we bridge the knowledge of diterpene chemical diversity, biosynthesis, and evolution from nonvascular mosses and liverworts to that known from vascular plants. ABSTRACT The diverse array of diterpenoid natural products stems from the ease of manipulating the promiscuity of diterpene cyclases.
Anita Berg   +2 more
wiley   +1 more source

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