Results 61 to 70 of about 27,515 (197)
Online Gambling Disorder Questionnaire (OGD-Q): An item r‘esponse theory examination
Addictive Behaviors Reports, 2022 Gambling disorder behaviours, such as one's preoccupation with gambling and/or mood modification due to gambling, have been proposed to differ in their diagnostic weight/importance, especially when informing diagnostic scales. Such potential differences are imperative to be considered to improve assessment accuracy. The latter is particularly important
V. Stavropoulos +4 more
openaire +5 more sources
Advanced Science, EarlyView.Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia +13 more
wiley +1 more source
Butorphanol protects PC12 cells against OGD/R-induced inflammation and apoptosis
Molecular Medicine Reports, 2020 The aim of the present study was to examine the effects of butorphanol on neural injury in an oxygen glucose deprivation/reoxygenation (OGD/R) model using PC12 cells, and to investigate whether mitochondrial apoptosis was involved in these effects.
Yang, Zijing +3 more
openaire +3 more sources
Advanced Science, EarlyView.6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi +12 more
wiley +1 more source
An Investigation on Users’ Perceptions of Open Government Data in Qatar
Human Behavior and Emerging TechnologiesThis study is aimed at evaluating users’ perceptions of open government data (OGD) in Qatar, addressing disparities between the perceived performance and perceived importance of OGD, and identifying the antecedents and consequences of OGD gaps.
Rima Charbaji El-Kassem, Ali Al-Kubaisi
doaj +1 more source
BMC Neuroscience, 2004 Background Ischemia within the optic nerve head (ONH) may contribute to retinal ganglion cell (RGC) loss in primary open angle glaucoma (POAG). Ischemia has been reported to increase neurotrophin and high affinity Trk receptor expression by CNS neurons ...
Clark Abbot F +2 more
doaj +1 more source
PLoS ONE, 2022 Providing access to non-confidential government data to the public is one of the initiatives adopted by many governments today to embrace government transparency practices.
Mimi Nurakmal Mustapa +2 more
doaj +1 more source
Linear and Geometric Mixtures - Analysis
, 2013 Linear and geometric mixtures are two methods to combine arbitrary models in data compression. Geometric mixtures generalize the empirically well-performing PAQ7 mixture.
Mattern, Christopher
core +1 more source
Back Again to the Future: A New Era for Cerebroprotection
Annals of Neurology, EarlyView.Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley +1 more source
E-democracy and values in information systems design [PDF]
, 2012 In this paper I demonstrate the utility of a Values in Design (VID) perspective for the assessment, the design and development of e-democracy tools. In the first part, I give some background information on Values in Design and Value-Sensitive Design and ...
Simon, Judith
core