Results 91 to 100 of about 5,940 (176)

8-Oxoguanine DNA Glycosylase1 conceals oxidized guanine in nucleoprotein-associated RNA of respiratory syncytial virus.

PLoS Pathogens
Respiratory syncytial virus (RSV), along with other prominent respiratory RNA viruses such as influenza and SARS-CoV-2, significantly contributes to the global incidence of respiratory tract infections.
Lang Pan, Ke Wang, Wenjing Hao, Yaoyao Xue, Xu Zheng, Ritwika S Basu, Tapas K Hazra, Azharul Islam, Yashoda Hosakote, Bing Tian, Matthieu G Gagnon, Xueqing Ba, Istvan Boldogh   +12 more
doaj   +1 more source

Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy

Molecular Medicine
Background 8-Oxoguanine DNA glycosylase (OGG1), a well-known DNA repair enzyme, has been demonstrated to promote lung fibrosis, while the specific regulatory mechanism of OGG1 during pulmonary fibrosis remains unclarified.
Wenjuan Wu, Hongxia Jia, Song Chen, Xinran Ma, Shuai Zhou, Lingxiao Qiu, Xinhui Wu, Ping Li, Heying Chu, Guojun Zhang   +9 more
doaj   +1 more source

Evaluation of 8-Oxoguanine DNA Glycosylase-1(OGG1) Serum Levels in Patients with Type2 Diabetes Mellitus

Wasit Journal for Pure Sciences
: Chronic hyperglycemia in type 2 diabetes mellitus leads to elevated oxidative stress. As a consequence, the accumulation of reactive oxygen species (ROS)may cause additional damage to various biological macromolecules, including DNA. The current study
Duaa Hussein Allawi Al-dulaimi
doaj   +1 more source

OGG1 wt Allele [PDF]

, 2020
openaire   +1 more source

DNA Oxidation and Expression of Repair Enzymes in Organ- Cultured Human Limbal Epithelium. [PDF]

Int J Mol Sci
Nicolaissen BO, Nguyen G, Beraki K, Azqueta A, Petrovski G, Moe MC, Krohn-Hansen D, Collins AR, Nicolaissen B, Lorenzo Y.   +9 more
europepmc   +1 more source

DNA base lesion-containing G-quadruplex mediates transcriptome reprogramming in EGFR-TKI resistance of non-small cell lung cancer. [PDF]

J Exp Clin Cancer Res
Jing X, Liu Z, Yang L, Xiong Y, Li S, Hang R, Yang X, Dai X, Li J, Yang J, Cheng Y, Jiang Z, Cao H, Kapranov P, Chen Q, Wang D, Guo W, Huang Z, Li M.   +18 more
europepmc   +1 more source

OGG1 increases exercise endurance via elevated skeletal muscle FGF21. [PDF]

J Biol Chem
Blaze B, Sharma P, Gupta BP, Mandal S, Komakula SSB, Anthony T, Marfo E, Sampath H.   +7 more
europepmc   +1 more source

Mitochondrial 8-Oxoguanine DNA Glycosylase 1-Mitochondrial Permeability Transition Pore Axis Drives Mitochondrial DNA Escape and Accelerates Osteoarthritis Progression. [PDF]

Research (Wash D C)
Huang S, Yu H, Qi W, Lin N, Chen J, Huang H, Hu P, Zhou Z, Zhang M, Ruan G, Xue S, Ding C.   +11 more
europepmc   +1 more source

OGG1 and MUTYH DNA Glycosylases, the Dynamic Duo Against 8-Oxoguanine DNA Lesion: Structure, Regulation, and Novel Emerging Roles. [PDF]

Biomolecules
Gómez-Ramírez AP, Malek M, García-González EG, Campos SE, Brieba LG, David SS, Trasviña-Arenas CH.   +6 more
europepmc   +1 more source

African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation. [PDF]

J Mol Cell Biol
Fan J, Yang J, Tian Z, Zhang X, Geng S, Luo J, Boldogh I, Zeng Q, Yin H, Guan G, Niu Q.   +10 more
europepmc   +1 more source