Results 131 to 140 of about 11,397 (216)

Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine [PDF]

, 2017
Aguilera-Aguirre, Leopoldo, Boldogh, István, Bácsi, Attila, Hajas, György, Hazra, Tapas K., Hegde, Muralidhar L., Mitra, Sankar, Radák, Zsolt, Sur, Sanjiv   +8 more
core   +1 more source

OGG1 wt Allele [PDF]

, 2020
openaire   +1 more source

2008 Progress Report on Brain Research [PDF]

, 2008
Highlights new research on various disorders, nervous system injuries, neuroethics, neuroimmunology, pain, sense and body function, stem cells and neurogenesis, and thought and memory.
Eve Marder, Mahlon R. DeLong, Michael S. Gazzaniga, Thomas Wichmann   +3 more
core  

Association between polymorphisms of OGG1, EPHA2 and age-related cataract risk: a meta-analysis [PDF]

, 2016

core   +1 more source

OGG1 inhibition as combination treatment for cancer therapy

, 2016
Novel anticancer therapies are needed to overcome drug resistance of chemotherapeutic drugs leading to tumor relapse. Combination therapy with target-specific drugs underlies great potential to increase the efficiency of chemotherapy. Increased DNA repair capacity is one of the resistance mechanism of chemotherapy drug cisplatin.
openaire   +1 more source

Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina.

Molecular vision, 2009
The retina is highly exposed to oxidative stress due to the high level of oxygen consumption in this tissue and its exposure to light. The main DNA base lesion generated by oxygen free radicals is 8-oxoguanine (8-oxoG). However, its presence in retinal cells and the mechanisms underlying its repair remain undetermined.8-oxoguanine DNA glycosylase (Ogg1)
Bigot, K., Leemput, J., Vacher, M., Campalans, Anna, Radicella, J. Pablo, Lacassagne, E., Provost, A., Masson, C., Menasche, M., Abitbol, M.   +9 more
openaire   +2 more sources

8-Oxoguanine: A Lesion, an Epigenetic Mark, or a Molecular Signal? [PDF]

Int J Mol Sci
Endutkin AV, Dvornikova AP, Zharkov DO.
europepmc   +1 more source

Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats. [PDF]

'Developmental programming', which occurs as a consequence of suboptimal in utero and early environments, can be associated with metabolic dysfunction in later life, including an increased incidence of cardiovascular disease and type 2 diabetes, and ...
Aiken, CE, Chen, JH, Fernandez-Twinn, DS, Hargreaves, IP, Neergheen, V, Ozanne, SE, Tarry-Adkins, JL   +6 more
core  

Base-excision repair increases DNA double-strand break clustering within heavy-ion tracks and modulates repair at δ-electron-induced breaks. [PDF]

Sci Rep
Schwan L, Averbeck NB, Durante M, Jakob B.   +3 more
europepmc   +1 more source

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1. [PDF]

RSC Chem Biol
Hank EC, D'Arcy-Evans ND, Scaletti ER, Benítez-Buelga C, Wallner O, Ortis F, Zhou K, Meng L, Del Prado A, Calvo P, Almlöf I, Wiita E, Nierlin K, Košenina S, Krämer A, Eddershaw A, Kehler M, Long M, Jemth AS, Dawson H, Stewart J, Dickey A, Astorga ME, Varga M, Homan EJ, Scobie M, Knapp S, Sastre L, Stenmark P, de Vega M, Helleday T, Michel M.   +31 more
europepmc   +1 more source