Results 41 to 50 of about 184,585 (308)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The effect of oils on the lymphatic absorption of DDT

Journal of Pharmacy and Pharmacology, 1982
Abstract Plasma concentrations of DDT were measured in conscious rats following oral administration in arachis oil, Miglyol 812 (fractionated coconut oil), liquid paraffin or as a fine suspension in water. The total absorption of DDT, calculated as the area under the plasma concentration time curve, was significantly greater for the ...
K J, Palin, C G, Wilson, S S, Davis, A J, Phillips   +3 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Intestinal barrier function and absorption in pigs after waeaning: a review

, 2011
Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Wijtten, P.J.A., Verstegen, M.W.A., Meulen, J., van der   +2 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Vitamin A equivalency of ß-carotene in healthy adults: limitation of the extrinsic dual-isotope dilution technique to measure matrix effect

, 2009
Data on the vitamin A equivalency of ß-carotene in food are inconsistent. We quantified the vitamin A equivalency (¿g) of ß-carotene in two diets using the dual-isotope dilution technique and the oral¿faecal balance technique.
Lieshout, M. van, Naber, T.H.J., Siebelink, E., Breemen, R.B., van, Versloot, P., Bouwman, C.A., Russel, F.G.M., van Breemen, R.B., Zhu, D., Hulshof, P.J., Naber, A.H.J., Lieshout, M., van, West, C.E., Hulshof, P.J.M., Loo-Bouwman, C.A. Van, van Lieshout, M., Schaafsma, G., Breemen, R.B. van   +17 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Simulation of the heat and mass transfer processes during the vacuum frying of potato chips [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2008
A fundamental two-dimensional model to predict the heat and mass transfer that occur during the vacuum frying of potato chips was solved using the Finite Element toolbox in MATLAB 6.1.
Ram Yamsaengsung, Charnchai Rungsee, Kulchanat Prasertsit   +2 more
doaj  

Application of Cogon Grass (Imperata cylindrica) as Biosorbent in Diesel-Filter System for Oil Spill Removal

Agronomy, 2021
Imperata cylindrica, often known as cogon grass, is a low-cost and useful sorbent for absorbing oil and optimising processes. The effects of temperature, time, packing density and oil concentration on oil absorption efficiency were investigated and ...
Farah Eryssa Khalid, Siti Aqlima Ahmad, Nur Nadhirah Zakaria, Noor Azmi Shaharuddin, Suriana Sabri, Alyza Azzura Azmi, Khalilah Abdul Khalil, Gayathiri Verasoundarapandian, Claudio Gomez-Fuentes, Azham Zulkharnain   +9 more
doaj   +1 more source