Results 91 to 100 of about 22,727 (219)
Aging Cell, Volume 24, Issue 11, November 2025.Efficient axonal Tau sorting requires the PRR2 domain but does not depend on AT8 or KXGS phosphorylation, the MT affinity, the C‐terminal repeat domains, or the N‐terminal tail of Tau. Human 0N4R‐Tau shows isoform‐specific interaction with modulators of synaptic plasticity involved in spine function under both normal and AD conditions.
Michael Bell‐Simons +7 more
wiley +1 more source
Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
Marine Drugs, 2012 The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP).
José J. Fernández +3 more
doaj +1 more source
Oceanography and Pacific Oyster Biochemical Composition in a Novel Oyster‐Growing Region
Aquaculture, Fish and Fisheries, Volume 5, Issue 5, October 2025.ABSTRACT The farming of Pacific oysters (Crassostrea [Magallana] gigas) is a rapidly growing industry in Alaska, where farms represent some of the highest latitude oyster cultivation efforts in the world. Little is known about the nearshore oceanography where Alaskan farms are located, or how the subarctic marine context influences oyster tissue ...
Rebecca Cates +8 more
wiley +1 more source
Toxins, 2015 Okadaic acid and its analogues are potent phosphatase inhibitors that cause Diarrheic Shellfish Poisoning (DSP) through the ingestion of contaminated shellfish by humans. This group of toxins is transmitted worldwide but the number of poisoning incidents
Marisa Silva +9 more
doaj +1 more source
Midline1 and the development of the cranial peripheral nervous system [PDF]
, 2008 Genetic abnormalities involving the skull and facial region account for around 1/3 of birth defects. Opitz BBB/G syndrome is one such disorder that gives rise to craniofacial malformations, as well as midline defects that cause gastrointestinal ...
Golding, Jon +2 more
core
AKT activation controls cell survival in response to HDAC6 inhibition. [PDF]
, 2016 HDAC6 is emerging as an important therapeutic target for cancer. We investigated mechanisms responsible for survival of tumor cells treated with a HDAC6 inhibitor.
Aboagye, EO +3 more
core +1 more source
Advanced Materials Interfaces, Volume 12, Issue 17, September 8, 2025.A novel electrochemical aptasensor enables the selective detection of lung cancer‐derived EVs by targeting the CD44 surface marker. The sensor uses a self‐assembled monolayer (SAM) for aptamer immobilization and achieves label‐free EV detection through electrochemical impedance spectroscopy.
Zarinah M. Amin +3 more
wiley +1 more source
Toxins, 2016 This study explores the effect of laboratory and industrial steaming on mussels with toxin concentrations above and below the legal limit. We used mild conditions for steaming, 100 °C for 5 min in industrial processing, and up to 20 min in small-scale ...
Inés Rodríguez +4 more
doaj +1 more source
PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. [PDF]
, 2019 Inflammation is an essential aspect of innate immunity but also contributes to diverse human diseases. Although much is known about the kinases that control inflammatory signaling, less is known about the opposing phosphatases.
Cohen Katsenelson, Ksenya +7 more
core +1 more source
Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts [PDF]
, 2001 Oncoprotein 18 (Op18) is a microtubule-destabilizing protein that is negatively regulated by phosphorylation. To evaluate the role of the three Op18 phosphorylation sites in Xenopus (Ser 16, 25, and 39), we added wild-type Op18, a nonphosphorylatable ...
Andersen +67 more
core +4 more sources