Results 81 to 90 of about 3,497 (175)

Machine Learning Integration Framework Constructs a Lactylation‐Associated Gene Signature to Improve Prognosis in Bladder Cancer

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Bladder cancer remains a significant challenge in oncology owing to its high recurrence rates and limited treatment options, particularly in cases of resistance to standard therapies. Aims Our study aimed to pinpoint a lactylation‐associated gene signature capable of predicting prognosis and providing important theoretical support ...
Jingsong Wang   +8 more
wiley   +1 more source

The Effect of Okadaic Acid on Cultured Tissues of Bivalves, Mytilus galloprovincialis and Crassostrea gigas

open access: yes, 1994
Okadaic acid, which is known to be a cause of the diarrhetic shellfish poisoning, was tested for its effect on the morphology of primary cultures established from two bivalve species, Mytilus galloprovincialis and Crassostrea gigas.
Ogata, Hiroshi   +9 more
core  

New Invertebrate Vectors of Okadaic Acid from the North Atlantic Waters—Portugal (Azores and Madeira) and Morocco

open access: yesToxins, 2015
Okadaic acid and its analogues are potent phosphatase inhibitors that cause Diarrheic Shellfish Poisoning (DSP) through the ingestion of contaminated shellfish by humans. This group of toxins is transmitted worldwide but the number of poisoning incidents
Marisa Silva   +9 more
doaj   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh   +4 more
wiley   +1 more source

Okadaic acid disrupts Golgi structure and impairs enzyme synthesis and secretion in the rat pancreas

open access: yes, 1996
Okadaic acid, a serine/threonine phosphatase inhibitor, has been shown to inhibit rat pancreatic enzyme secretion by interference with late processes in stimulus-secretion coupling.
B. Agricola   +4 more
core   +1 more source

Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)

open access: yesMarine Drugs, 2012
The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP).
José J. Fernández   +3 more
doaj   +1 more source

An idiotypic-anti-idiotypic competitive immunoassay for quantitation of okadaic acid

open access: yes, 1992
A competitive indirect enzyme-linked immunosorbent assay for the measurement of okadaic acid, a marine toxin, was developed. The assay uses a murine monoclonal anti-idiotypic antibody bearing an internal image of okadiac acid epitope to capture an anti ...
Quilliam, Michael A.   +5 more
core   +1 more source

Evaluation of the Impact of Mild Steaming and Heat Treatment on the Concentration of Okadaic Acid, Dinophysistoxin-2 and Dinophysistoxin-3 in Mussels

open access: yesToxins, 2016
This study explores the effect of laboratory and industrial steaming on mussels with toxin concentrations above and below the legal limit. We used mild conditions for steaming, 100 °C for 5 min in industrial processing, and up to 20 min in small-scale ...
Inés Rodríguez   +4 more
doaj   +1 more source

Studies on the release of okadaic acid in Prorocentrum lima and the methodological optimization of okadaic acid purification

open access: yes, 2007
本研究探討黑海綿酸的提純最適化,在研究初期發現藻細胞在培養至穩定期後,釋放黑海綿酸到培養液中的濃度大量提高,不利於從藻細胞內提純黑海綿酸,此時針對培養液中黑海綿酸的提純,較從藻細胞後內提純更簡單,因此本研究以合成吸附樹脂SP825吸附培養液中的黑海綿酸後,再行脫附提純。SP825對黑海綿酸吸附實驗中,發現SP825吸附承載量至少為4.736 mg/g,而SP825對黑海綿酸的脫附率可達96.9 %,整個操作不僅能完全吸附培養基中的黑海綿酸,並可利用甲醇來達到脫附毒素的目的,增加量化生產時濃縮操作的方便性,
Wu, Jain-Shin, 吳建欣
core  

Bysmatrum granulosum sp. nov., a new benthic dinoflagellate from the southwestern Indian Ocean [PDF]

open access: yes, 2001
A new benthic marine dino¯agellate, Bysmatrum granulosum Ten-Hage, Turquet, Quod & Couté, sp. nov., was obtained from sediment and coral samples from sites of La Réunion Island (SW Indian Ocean). This new species is described and illustrated by light and
LOÏC TEN-HAGE   +7 more
core   +1 more source

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