Results 81 to 90 of about 22,039 (219)
Okadaic acid–induced apoptosis in malignant glioma cells [PDF]
Neurosurgical Focus, 2003 Object Okadaic acid (OA), a potent protein phosphatase inhibitor, has been known to induce apoptosis in a variety of cell types. The authors attempted to characterize further this model by identifying proteins involved in this form of programmed cell death.
Bimal G, Rami +3 more
openaire +2 more sources
Cancer Medicine, Volume 15, Issue 1, January 2026.ABSTRACT Background Bladder cancer remains a significant challenge in oncology owing to its high recurrence rates and limited treatment options, particularly in cases of resistance to standard therapies. Aims Our study aimed to pinpoint a lactylation‐associated gene signature capable of predicting prognosis and providing important theoretical support ...
Jingsong Wang +8 more
wiley +1 more source
Marine Drugs, 2008 Okadaic acid (1) (OA) and its congeners are mainly responsible for diarrhetic shellfish poisoning (DSP) syndrome. The presence of several OA derivatives have already been confirmed in Prorocentrum and Dinophysis spp.
José J. Fernández +5 more
doaj
Toxins, 2014 Harmful algal blooms expose humans and animals to microcystins (MCs) through contaminated drinking water. While hepatotoxicity following acute exposure to MCs is well documented, neurotoxicity after sub-lethal exposure is poorly understood. We developed
Caroline E. Moore +2 more
doaj +1 more source
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Toxins, 2016 ERETIC2 (Electronic Reference To access In vivo Concentrations 2) based on PULCON (Pulse Length–based Concentration determination) methodology is a quantitative NMR (qNMR) using an external standard.
Ryuichi Watanabe +7 more
doaj +1 more source
The effects of immune challenge on phenoloxidase activity in locust salivary glands in vitro [PDF]
, 2008 Homogenates of salivary glands from Locusta migratoria possess phenoloxidase (PO) activity. This study investigates the activation of prophenoloxidase (PPO) in these glands in vitro. When freshly dissected salivary glands from L. migratoria are incubated
Ashida +14 more
core +1 more source
Plant Direct, Volume 10, Issue 1, January 2026.ABSTRACT Despite being one of the few bona fide plant tyrosine phosphatases, the Arabidopsis thaliana Rhizobiales‐like phosphatase 2 (RLPH2) has no known substrates. Utilizing phospho‐proteomics, we identified the activation loop phospho‐tyrosine of several A. thaliana D‐group mitogen‐activated protein kinases (MPKs) as potential RLPH2 substrates.
Anne‐Marie Labandera +8 more
wiley +1 more source
Diverse Bacterial PKS Sequences Derived From Okadaic Acid-Producing Dinoflagellates
Marine Drugs, 2008 Okadaic acid (OA) and the related dinophysistoxins are isolated from dinoflagellates of the genus Prorocentrum and Dinophysis. Bacteria of the Roseobacter group have been associated with okadaic acid producing dinoflagellates and have been previously ...
Kathleen S. Rein +4 more
doaj
Shape oscillations of human neutrophil leukocytes: characterization and relationship to cell motility [PDF]
, 1996 When neutrophil leukocytes are stimulated by chemotactic factors or by substratum contact, they change their shape. Shape changes are a prerequisite for cellular migration and typically involve the extrusion of thin, veil-like lamellipods and the ...
Coates, Thomas D. +2 more
core