Results 91 to 100 of about 2,519,072 (211)
, 2007 本研究探討黑海綿酸的提純最適化，在研究初期發現藻細胞在培養至穩定期後，釋放黑海綿酸到培養液中的濃度大量提高，不利於從藻細胞內提純黑海綿酸，此時針對培養液中黑海綿酸的提純，較從藻細胞後內提純更簡單，因此本研究以合成吸附樹脂SP825吸附培養液中的黑海綿酸後，再行脫附提純。SP825對黑海綿酸吸附實驗中，發現SP825吸附承載量至少為4.736 mg/g，而SP825對黑海綿酸的脫附率可達96.9 %，整個操作不僅能完全吸附培養基中的黑海綿酸，並可利用甲醇來達到脫附毒素的目的，增加量化生產時濃縮操作的方便性，
Wu, Jain-Shin, 吳建欣
core
Okadaic acid stimulates carnitine palmitoyltransferase I activity and palmitate oxidation in isolated rat hepatocytes [PDF]
, 1991 Okadaic acid increased in parallel with carnitine palmitoyltransferase I activity and the rate of palmitate oxidation in isolated rat hepatocytes. Nevertheless, okadaic acid had no significant effect on the rate of octanoate oxidation. Maximal effects of
Castro, José +3 more
core +1 more source
Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
Marine Drugs, 2012 The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP).
José J. Fernández +3 more
doaj +1 more source
Okadaic acid disrupts Golgi structure and impairs enzyme synthesis and secretion in the rat pancreas
, 1996 Okadaic acid, a serine/threonine phosphatase inhibitor, has been shown to inhibit rat pancreatic enzyme secretion by interference with late processes in stimulus-secretion coupling.
B. Agricola +4 more
core +1 more source
Bysmatrum granulosum sp. nov., a new benthic dinoflagellate from the southwestern Indian Ocean [PDF]
, 2001 A new benthic marine dino¯agellate, Bysmatrum granulosum Ten-Hage, Turquet, Quod & Couté, sp. nov., was obtained from sediment and coral samples from sites of La Réunion Island (SW Indian Ocean). This new species is described and illustrated by light and
LOÏC TEN-HAGE +7 more
core +1 more source
Toxins, 2015 Okadaic acid and its analogues are potent phosphatase inhibitors that cause Diarrheic Shellfish Poisoning (DSP) through the ingestion of contaminated shellfish by humans. This group of toxins is transmitted worldwide but the number of poisoning incidents
Marisa Silva +9 more
doaj +1 more source
An idiotypic-anti-idiotypic competitive immunoassay for quantitation of okadaic acid
, 1992 A competitive indirect enzyme-linked immunosorbent assay for the measurement of okadaic acid, a marine toxin, was developed. The assay uses a murine monoclonal anti-idiotypic antibody bearing an internal image of okadiac acid epitope to capture an anti ...
Quilliam, Michael A. +5 more
core +1 more source
Toxins, 2016 This study explores the effect of laboratory and industrial steaming on mussels with toxin concentrations above and below the legal limit. We used mild conditions for steaming, 100 °C for 5 min in industrial processing, and up to 20 min in small-scale ...
Inés Rodríguez +4 more
doaj +1 more source
Bioscience, Biotechnology, and Biochemistry, 1994 The specificity of five mouse monoclonal antibodies to okadaic acid was studied for use in an enzyme-linked immunosorbent assay of okadaic acid and its analogs. OA8-2 and OA22-22 antibodies (IgG2a-kappa), which bind more strongly to dinophysistoxin-1 and 7-O-palmitoyl-dinophysistoxin-1 than to okaic acid or 7-O-palmitoyl-okadaic acid in 50% aqueous ...
Matsuura, Shiro +2 more
openaire +2 more sources
Okadaic acid uncouples myosin light chain phosphorylation and tension in smooth muscle [PDF]
, 1990 Tracheal smooth muscle precontracted with carbachol relaxes upon the addition of 3 μM okadaic add. Although cytosolic Ca2+ concentrations decrease, myosin light chain remains highly phosphorylated (50%).
Tansey, M.G. +9 more
core +1 more source