Okadaic acid co−induces vimentin expression and cell cycle arrest in MPC−11 mouse plasmacytoma cells
, 1994 he effect of the tumor promoter okadaic acid on cell cycle progression and on vimentin expression in MPC−11 mouse plasmacytoma cells was compared with that of the tumor promoter 12−O−tetradecanoylphorbol−13−acetate (TPA).
P. Traub +13 more
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Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans [PDF]
, 2001 Chicken xenobiotic receptor, pregnane X receptor, and constitutive androstane receptor are orphan nuclear receptors that have recently been discovered to regulate drug- and steroid-mediated induction of hepatic cytochromes P450 (CYP).
Stockli, J. +4 more
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Formal Total Synthesis of Okadaic Acid via Regiocontrolled Gold(I)-Catalyzed Spiroketalizations
, 2016 Both C19 and C34 spiroketal domains of okadaic acid were assembled using gold(I) chloride catalyzed spiroketalizations, and the two resulting fragments were coupled to give the C15−C38 fragment of okadaic acid, a known intermediate for the total ...
Chao Fang (456315) +2 more
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Frontiers in Aging NeuroscienceIntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by decreased memory and cognitive impairment. Abnormal tau hyperphosphorylation ultimately forms neurofibrillary tangles, which is one of the most important ...
Jiahui Li +6 more
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Estudo da bioacumulação e eliminação do ácido ocadáico, produzido pelo dinoflagelado Prorocentrum lima, em mexilhões da espécie Perna perna (Mollusca:Bivalvia) [PDF]
, 2000 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Nos últimos anos, o fenômeno conhecido como "maré vermelha", caracterizado por uma massiva proliferação de organismos pertencentes ao fitoplâncton que podem ser tóxicos ...
Lemieszek, Márcia Bonow
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Фактори експериментальної еволюції організмів, 2015 Aim. Okadaic acid (OA) strongly inhibits protein serine/threonine phosphatases PP1 and PP2A/2B. In comparison with the other inhibitors the inhibitory effect of OA is strongest for PP2A, followed by PP1, and then PP2B.
Д. А. Самофалова +2 more
doaj
Current situation on analysis of marine toxins
Reviews in Analytical Chemistry, 2013 Marine toxins are a food safety concern worldwide. This review discusses current analytical methods for those toxins that are legally regulated in Europe, namely domoic acid, saxitoxin, okadaic acid, yessotoxin, pectenotoxin and azaspiracids, and all ...
Botana Ana M. +4 more
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Okadaic acid stimulates IGF-II receptor translocation and inhibits insulin action in adipocytes
, 1993 Okadaic acid, an inhibitor of protein phosphatases 2A and 1, stimulates glucose transport in muscle and fat cells, suggesting that serine/threonine phosphorylation steps are involved in the translocation of glucose transporters. Here we have investigated
E. Van Obberghen +4 more
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The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) [PDF]
Invertebrate Survival Journal, 2006 We describe the morpho-functional effects of different concentrations of okadaic acid (OA) on specimens of Enchytraeus crypticus. The results demonstrate that this experimental model is very sensitive to the treatment and presents time- and dose-related ...
A Franchini, M Marchetti
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, 2006 A cis-isomer of a C8-diol ester of okadaic acid (1) was isolated during large-scale purification of pectenotoxins (PTXs) from extracts of Dinophysis acuta collected from the west coast of South Island, New Zealand.
Lincoln MacKenzie, A. +9 more
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