Results 101 to 110 of about 14,228 (214)
Toxins, 2015 Okadaic acid and its analogues are potent phosphatase inhibitors that cause Diarrheic Shellfish Poisoning (DSP) through the ingestion of contaminated shellfish by humans. This group of toxins is transmitted worldwide but the number of poisoning incidents
Marisa Silva +9 more
doaj +1 more source
Bysmatrum granulosum sp. nov., a new benthic dinoflagellate from the southwestern Indian Ocean [PDF]
, 2001 A new benthic marine dino¯agellate, Bysmatrum granulosum Ten-Hage, Turquet, Quod & Couté, sp. nov., was obtained from sediment and coral samples from sites of La Réunion Island (SW Indian Ocean). This new species is described and illustrated by light and
LOÏC TEN-HAGE +7 more
core +1 more source
Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
Marine Drugs, 2012 The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP).
José J. Fernández +3 more
doaj +1 more source
Selection and Identification of DNA Aptamers against Okadaic Acid for Biosensing Application [PDF]
, 2016 This work describes the selection and identification of DNA aptamers that bind with high affinity and specificity to okadaic acid (OA), a lipophilic marine biotoxin that accumulates in shellfish.
Mohamed Siaj (1623370) +4 more
core +1 more source
Toxins, 2016 This study explores the effect of laboratory and industrial steaming on mussels with toxin concentrations above and below the legal limit. We used mild conditions for steaming, 100 °C for 5 min in industrial processing, and up to 20 min in small-scale ...
Inés Rodríguez +4 more
doaj +1 more source
Bioscience, Biotechnology, and Biochemistry, 1994 The specificity of five mouse monoclonal antibodies to okadaic acid was studied for use in an enzyme-linked immunosorbent assay of okadaic acid and its analogs. OA8-2 and OA22-22 antibodies (IgG2a-kappa), which bind more strongly to dinophysistoxin-1 and 7-O-palmitoyl-dinophysistoxin-1 than to okaic acid or 7-O-palmitoyl-okadaic acid in 50% aqueous ...
Matsuura, Shiro +2 more
openaire +2 more sources
Effect of Okadaic Acid On Membrane-protein Phosphorylation In Human Erythrocytes [PDF]
, 1993 Okadaic acid, penetrating the human erythrocytes, almost completely inhibits P-Ser-protein phosphatase activity, whereas it unaffects Ser/Thr-protein kinase activity (casein kinases CKI and CKII), thus promoting a marked increase of the endogenous Ser ...
CLARI, GIULIO +4 more
core +1 more source
Is Protein Phosphatase Inhibition Responsible for the Toxic Effects of Okadaic Acid in Animals?
Toxins, 2013 Okadaic acid (OA) and its derivatives, which are produced by dinoflagellates of the genera Prorocentrum and Dinophysis, are responsible for diarrhetic shellfish poisoning in humans.
Rex Munday
doaj +1 more source
Okadaic acid uncouples myosin light chain phosphorylation and tension in smooth muscle [PDF]
, 1990 Tracheal smooth muscle precontracted with carbachol relaxes upon the addition of 3 μM okadaic add. Although cytosolic Ca2+ concentrations decrease, myosin light chain remains highly phosphorylated (50%).
Tansey, M.G. +9 more
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Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans [PDF]
, 2001 Chicken xenobiotic receptor, pregnane X receptor, and constitutive androstane receptor are orphan nuclear receptors that have recently been discovered to regulate drug- and steroid-mediated induction of hepatic cytochromes P450 (CYP).
Stockli, J. +4 more
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