Results 111 to 120 of about 3,497 (175)
, 1991 The sensitivity of red blood cells containing hemoglobins S and C to activation of K-Cl cotransport by osmotic swelling and acidification was reduced by okadaic acid, a specific protein phosphatase inhibitor.
J. A. Whitney +4 more
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reservedIn the context of One Health approach, which recognizes the interconnection between human, animal, and environmental health, marine biotoxins pose an increasing threat to food safety. Among these ones, okadaic acid (OA), a potent lipophilic toxin
CAROLLO, GIORGIA
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Selection and Identification of DNA Aptamers against Okadaic Acid for Biosensing Application
, 2016 This work describes the selection and identification of DNA aptamers that bind with high affinity and specificity to okadaic acid (OA), a lipophilic marine biotoxin that accumulates in shellfish.
Mohamed Siaj (1623370) +4 more
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Effect of Okadaic Acid On Membrane-protein Phosphorylation In Human Erythrocytes
, 1993 Okadaic acid, penetrating the human erythrocytes, almost completely inhibits P-Ser-protein phosphatase activity, whereas it unaffects Ser/Thr-protein kinase activity (casein kinases CKI and CKII), thus promoting a marked increase of the endogenous Ser ...
CLARI, GIULIO +4 more
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Estudo da bioacumulação e eliminação do ácido ocadáico, produzido pelo dinoflagelado Prorocentrum lima, em mexilhões da espécie Perna perna (Mollusca:Bivalvia) [PDF]
, 2000 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Nos últimos anos, o fenômeno conhecido como "maré vermelha", caracterizado por uma massiva proliferação de organismos pertencentes ao fitoplâncton que podem ser tóxicos ...
Lemieszek, Márcia Bonow
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Okadaic acid uncouples myosin light chain phosphorylation and tension in smooth muscle
, 1990 Tracheal smooth muscle precontracted with carbachol relaxes upon the addition of 3 μM okadaic add. Although cytosolic Ca2+ concentrations decrease, myosin light chain remains highly phosphorylated (50%).
Tansey, M.G. +9 more
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Expedient Access to the Okadaic Acid Architecture: A Novel Synthesis of the C1−C27 Domain
, 2016 A newly designed synthetic entry to the C1−C27 domain of okadaic acid has been developed. This incorporates substantial improvements in the preparations of the key okadaic acid building blocks representing the C3−C8, C9−C14, and C16−C27 portions.
Rebecca A. Urbanek (2004700) +3 more
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Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism
, 1989 Okadaic acid is a polyether derivative of 38-carbon fatty acid1, and is implicated as the causative agent of diarrhetic shellfish poisoning2. It is a potent tumour promoter that is not an activator of protein kinase C (ref.
D. Carling +13 more
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Okadaic acid does not impair T regulatory cell mediated suppression of CD4 effector cells.
, 2017 (a) Teff and Tregs were isolated from the lymph nodes and spleen of FoxP3-GFP mice. Cells were co-cultured at indicated ratios in the presence of antigen presenting cells and 0.15 μg/mL anti-CD3 for 96 hours +/- okadaic acid.
Kodi Ravichandran (3818341) +3 more
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, 2009 : To investigate the role of protein hyperphosphorylation in plant cells, the effect of okadaic acid, a specific inhibitor of protein phosphatases PPI and PP2A, on the general morphology of Arabidopsis thaliana primary roots and the structural-functional
Sheremet, Ya. A. +3 more
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