Generation of Internal-Image Functional Aptamers of Okadaic Acid via Magnetic-Bead SELEX
Okadaic acid (OA) is produced by Dinophysis and Prorocentrum dinoflagellates and primarily accumulates in bivalves, and this toxin has harmful effects on consumers and operators. In this work, we first report the use of aptamers as novel non-toxic probes
Chao Lin +12 more
doaj +1 more source
Okadaic acid potentiates heat-induced activation of erk2
Subjecting exponentially growing HeLa cells to heat shock at 45 degrees C for 30 min leads to retarded migration of erk1 and erk2, as revealed on immunoblots indicating their activation. Renaturation gels confirmed activation of erk2 but not erk1. Treatment of cells with okadaic acid (OA) alone marginally upregulated erk1 and erk2, whereas simultaneous
Heider, Harald, Widmer, Hans R.
openaire +2 more sources
The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) [PDF]
We describe the morpho-functional effects of different concentrations of okadaic acid (OA) on specimens of Enchytraeus crypticus. The results demonstrate that this experimental model is very sensitive to the treatment and presents time- and dose-related ...
A Franchini, M Marchetti
doaj +1 more source
Evaluación del modo de acción de toxinas de dinoflagelados y cianobacterias en células hepáticas [PDF]
El mar es fuente de buena parte de los alimentos que consume el ser humano. Además del agua marina, el hombre también se beneficia, de diversas maneras, de los recursos de agua dulce.
López Alonso, Henar
core +1 more source
Proteome and phospho-proteome study of Molm-13 cell line in Acute Myeloid Leukemia (AML) [PDF]
Curs 2015-2016The main goal of this thesis was to study the changes in the proteome of Molm-13 cells from Acute Myeloid Leukemia when treated with a proliferation and cell differentiation inductor (FLT3 ligand) and with an apoptosis inductor (Okadaic ...
Calvi Molina, Carlotta
core
Midline1 and the development of the cranial peripheral nervous system [PDF]
Genetic abnormalities involving the skull and facial region account for around 1/3 of birth defects. Opitz BBB/G syndrome is one such disorder that gives rise to craniofacial malformations, as well as midline defects that cause gastrointestinal ...
Golding, Jon +2 more
core
Full activation of the rat oocyte by protein synthesis inhibition requires protein phosphatase activity [PDF]
The rat oocyte provides an interesting system in which to dissect the control mechanisms involved in the transition between a meiotic M phase and a mitotic interphase. In this study, we show that in rat oocytes activated parthenogenetically by puromycin,
Maro, Bernard +2 more
core
Okadaic Acid Is at Least as Toxic as Dinophysistoxin-1 after Repeated Administration to Mice by Gavage. [PDF]
Park SY +6 more
europepmc +1 more source
Okadaic Acid Detection through a Rapid and Sensitive Amplified Luminescent Proximity Homogeneous Assay. [PDF]
Qin Y +7 more
europepmc +1 more source
A Sensitive Fluorescence Polarization Immunoassay for the Rapid Detection of Okadaic Acid in Environmental Waters. [PDF]
Hendrickson OD +4 more
europepmc +1 more source

