Results 61 to 70 of about 22,727 (219)
Detection of diarrheal shellfish toxins
Reviews in Analytical Chemistry, 2022 Seafood poisoning outbreaks are often caused by biotoxins generated by harmful algal blooms. Shellfish toxins, mainly derived from phytoplankton, cause diarrhea and poisoning in humans who consume contaminated seafood. Many studies suggest that diarrheal
Xu Rui +3 more
doaj +1 more source
Sensitive time-resolved fluoroimmunoassay for the quantitative detection of okadaic acid
Frontiers in Marine Science, 2022 Okadaic acid (OA) is a biotoxin from marine microalgae and widely present in shellfish, which severely affects the seafood safety. Therefore, it is essential to establish a highly sensitive OA analysis and detection method.
Yuan Qin +9 more
doaj +1 more source
Cell cycle regulation of a Xenopus Wee1-like kinase [PDF]
, 1995 Using a polymerase chain reaction-based strategy, we have isolated a gene encoding a Wee1-like kinase from Xenopus eggs. The recombinant Xenopus Wee1 protein efficiently phosphorylates Cdc2 exclusively on Tyr- 15 in a cyclin-dependent manner.
Coleman, Thomas R. +2 more
core
Regulated internalization of caveolae [PDF]
, 1994 Caveolae are specialized invaginations of the plasma membrane which have been proposed to play a role in diverse cellular processes such as endocytosis and signal transduction.
Joggerst, B., Parton, R. G., Simons, K.
core +4 more sources
Aging Cell, Volume 25, Issue 1, January 2026.P62‐TIF‐IA–mediated regulation of senescence and ageing. In healthy tissue, p62 facilitates TIF‐IA turnover. Upon senescence induction, ATM activation increases TIF‐IA phosphorylation at S44, reducing its p62 binding and causing TIF‐IA accumulation.
Hazel C. Thoms +17 more
wiley +1 more source
Use of Okadaic Acid to Identify Relevant Phosphoepitopes in Pathology: A Focus on Neurodegeneration
Marine Drugs, 2013 Protein phosphorylation is involved in the regulation of a wide variety of physiological processes and is the result of a balance between protein kinase and phosphatase activities. Biologically active marine derived compounds have been shown to represent
Jesús Avila +2 more
doaj +1 more source
Molecular Control of the Amount, Subcellular Location and Activity State of Translation Elongation Factor 2 (eEF-2) in Neurons Experiencing Stress [PDF]
, 2013 Eukaryotic elongation factor 2 (eEF-2) is an important regulator of the protein translation machinery wherein it controls the movement of the ribosome along the mRNA.
Argüelles-Castilla, Sandro +5 more
core +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.ABSTRACT Background Type 2 diabetes mellitus (T2D) arises from the interplay between peripheral insulin resistance and pancreatic β‐cell dysfunction, ultimately leading to impaired glucose utilization and chronic hyperglycemia. Despite therapeutic advances, the multifactorial nature of T2D continues to demand the development of novel treatment ...
Sang R. Lee +9 more
wiley +1 more source
Journal of Neuroinflammation, 2021 Background Inflammation undermines multiple forms of neuroplasticity. Although inflammation and its influence on plasticity in multiple neural systems has been extensively studied, its effects on plasticity of neural networks controlling vital life ...
Arash Tadjalli +3 more
doaj +1 more source
Transformation of a marine toxic polyether, okadaic acid. [PDF]
Agricultural and Biological Chemistry, 1988 Natural okadaic acid 1 was transformed into the 7, 24, 27-tri-0-benzyl-l, 2-acetonide derivative (4) in a 66% overall yidd. The corresponding synthetic derivative (4) was identified with this authentic sample.
Yoshiyasu Ichikawa +2 more
openaire +2 more sources