Results 81 to 90 of about 27,607 (170)

Developing a Polygenic Risk Score for Weight Gain in People Treated for Psychosis—Application in a Real‐World Setting

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 2, March 2026.
ABSTRACT Introduction Genetic factors are thought to play an important role in antipsychotic‐induced weight gain (AIWG). Polygenic risk scores (PRS) could provide a measure of genetic predisposition to antipsychotic drug induced weight gain (AIWG).We conducted a study to examine how a PRS, generated using SNPs, identified from a recent meta‐analysis ...
Adrian Heald, Yasitha Illangasekera, Camila Marcelino Loureiro, Mark Shakespeare, Adam Jameson, Adrian Phillipson, Gavin P. Reynolds, Caroline Dalton   +7 more
wiley   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, Volume 12, Issue 1, Page 3-37, Spring 2026.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Bioanalytical method development and validation for the simultaneous estimation of Olanzapine and Samidorphan in rabbit plasma by using HPLC–MS/MS and application to pharmacokinetic study

Future Journal of Pharmaceutical Sciences
Background Samidorphan is an opioid antagonist while Olanzapine is an effective medication for schizophrenia and bipolar disorder. A unique and accurate MS/HPLC approach due to simultaneous measurement of Olanzapine and Samidorphan is, therefore, more ...
Rambabu Kantipudi, Sugandha Kumar Pavuluri   +1 more
doaj   +1 more source

The Efficacy of Lacosamide in the Treatment of Delirium Complicated With Ileus: Four Cases

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Delirium in elderly patients is difficult to treat when complicated by ileus. This report describes three cases of antipsychotic‐induced paralytic ileus successfully managed with lacosamide without severe adverse effects. Lacosamide's pharmacological profile suggests it may be a safe treatment option for delirium tremens in older patients.
Shinji Sato
wiley   +1 more source

Catatonia an Unexpected Side Effect of Electroconvulsive Therapy: A Case Report

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
This case report highlights an unexpected development of catatonia following electroconvulsive therapy in a patient with schizoaffective disorder. The catatonia resolved promptly after discontinuing psychotropic interventions, emphasizing the need for careful monitoring during ECT, especially in patients with complex psychiatric histories.
Fatemeh sheikhmoonesi, Behnam Abbasi, Tahoura Sedighi Barforoushi, Ebrahim Khoshnama   +3 more
wiley   +1 more source

Suicide attempt and paranoia persisting for 28 days following heavy delta‐9‐tetrahydrocannabinolic acid and tetrahydrocannabinol use: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Cannabis contains various cannabinoids, with Δ9‐tetrahydrocannabinol (Δ9‐THC) being the primary psychoactive compound. A non‐psychoactive precursor called Δ9‐tetrahydrocannabinolic acid (THC‐A) is converted to Δ9‐THC slowly over time or rapidly when heated. Cannabis use is linked to psychotic outcomes, with increased risk associated
Daniel Greer, Prithula Dey, Caitlin E. Kulig   +2 more
wiley   +1 more source

A case of diverse psychiatric and functional impairments following immune checkpoint inhibitor therapy

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Immune checkpoint inhibitors (ICIs) can cause a range of immune‐related adverse events (irAEs), including rare neuropsychiatric complications. However, these events often present with diverse and non‐specific symptoms, making diagnosis difficult.
Takako Ikegami, Ryoichi Sadahiro, Junji Yamaguchi, Eri Nishikawa, Saho Wada, Tatsuto Terada, Rika Nakahara, Hiromichi Matsuoka   +7 more
wiley   +1 more source

A case of marked improvement in pareidolia in untreated schizophrenia following antipsychotic treatment

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Pareidolia, the tendency to perceive meaningful images within ambiguous visual patterns, is commonly observed in neurodegenerative disorders and schizophrenia. Owing to the limited number of studies, the characteristics of pareidolia accompanying schizophrenia remain unclear.
Tomonobu Kato, Eiichi Seki, Tadanori Kumasaka, Takashi Tsujii, Daiki Mochizuki, Hisashi Kida, Shigeru Nikkuni, Masafumi Mizuno, Kei Sakuma   +8 more
wiley   +1 more source

Initial dosage optimization of olanzapine in patients with bipolar disorder based on model-informed precision dosing: a study from the real world

Frontiers in Pharmacology
ObjectivesOlanzapine is used for treating bipolar disorder (BPD); however, the optimal initial dosing regimen is unclear. The present study aimed to investigate the optimal olanzapine initial dosage in patients with BPD via model-informed precision ...
Xiao Chen, Ke Hu, Hao-Zhe Shi, Liang Chen, Yi-Jia Zhang, Su-Mei He, Cun Zhang, Dong-Dong Wang   +7 more
doaj   +1 more source

Asenapine for delirium in patients with cancer: A scoping review

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract This scoping review mapped the existing literature on the application of asenapine for delirium management in patients with cancer, including prevention and treatment, while summarizing current research trends. The review followed the methodological framework proposed by Arksey and O'Malley and was reported in accordance with the Preferred ...
Tetsuro Ishida, Makoto Kobayakawa, Jun Kako, Yoshinobu Matsuda, Ryoichi Sadahiro, Hitoshi Tanimukai   +5 more
wiley   +1 more source