Factors affecting work ability and influencing early retirement decisions of older employees: an attempt to integrate the existing approaches. [PDF]
Int J Occup Med Environ Health, 2022 Woźniak B +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
Professional Development of Older Employees in Small and Medium Enterprises
Management and Business Administration. Central Europe, 2015 Purpose: The aim of the paper is to present and assess professional development opportunities for older employees in SME. Methodology: In the process of desk research, the author has discerned a number of characteristics of training activities conducted
Renata Trochimiuk
doaj
Medical rehabilitation of older employees with migrant background in Germany: Does the utilization meet the needs? [PDF]
PLoS One, 2022 Schröder CC, Breckenkamp J, du Prel JB.
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Management of Chronic Musculoskeletal Disorders in the Workplace from the Perspective of Older Employees: A Mixed Methods Research Study. [PDF]
Int J Environ Res Public Health, 2022 Skamagki G +3 more
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
The influence of chronic diseases and poor working conditions in working life expectancy across educational levels among older employees in the Netherlands. [PDF]
Scand J Work Environ Health, 2022 Schram JLD +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Ageism, Job Engagement, Negative Stereotypes, Intergenerational Climate, and Life Satisfaction among Middle-Aged and Older Employees in a University Setting. [PDF]
Int J Environ Res Public Health, 2022 McConatha JT, Kumar VK, Magnarelli J.
europepmc +1 more source