Results 71 to 80 of about 2,137,737 (281)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Older Women's Project Newsletter (Summer, 1991)

open access: yes, 1991
A newsletter focused on issues relevant to older women, particularly prejudice and discrimination.
Older Women's Project
core   +1 more source

Navigating the future

open access: yes, 2003
Annual; Dec. 31, 2002-; Title varies slightly.; Vol. for 2003- are for the years ended Dec. 31, 2003 & 2002-; Prepared under the direction of the OPERS Finance Division.; Harvested from the web on 7/25 ...
Ohio Public Employees Retirement System.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Effect of Training on an Ageing Workforce’s Attitude to Digital Transformation of a Communications Company [PDF]

open access: yesBusiness & IT
The rapid pace of technological change has significant implications for the modern workforce, particularly for organizations with an aging employee population. This study sought to explore the notion that a workforce nearing retirement are not interested
Sunil Piyarlall, Willem Bester
doaj   +1 more source

Hiring older employees: Do incentives of early retirement channels matter? [PDF]

open access: yes
We examine the impact of a Finnish reform in the 1990s that restricted the use of particular early retirement channels, unemployment pension and individual early retirement, and simultaneously changed the rules of firm size related experience rating in ...
Ilmakunnas, Pekka, Ilmakunnas, Seija
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Age management in Slovenian enterprises: the viewpoint of older employees [PDF]

open access: yesZbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2010
The main aim of this research is to highlight age management within Slovenian enterprises from the viewpoint of older employees by finding out what influences older employees to decide “should I stay or should I go”. The empirical research methodology is
Jana Žnidaršič
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The role and future development of supportive housing for older people in Ireland [PDF]

open access: yes, 2007
This report presents the results of a study to investigate the role and future development of supportive housing for older people in Ireland. For purposes of the study, supportive housing was defined as group or sheltered housing schemes for older ...
Dolphin, Ciaran   +2 more
core   +1 more source

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