Results 61 to 70 of about 2,137,737 (281)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Organizational identification among Brazilian public employees: a study of the cultural sector [PDF]
Revista Brasileira de Gestão De Negócios, 2017 Purpose – This study aims to understand the identification of public employees with the organizations in which they work by analyzing its determinants and consequences, in order to subsidize human resource management policies within these organizations.
Flávia de Souza Costa Neves Cavazotte +2 more
doaj +1 more source
Why Training Older Employees is Less Effective [PDF]
SSRN Electronic Journal, 2011 This paper shows that training of older employees is less effective. Training effectiveness is measured with respect to key dimensions such as career development, earnings, adoption of new skills, flexibility or job security. Older employees also pursue less ambitious goals with their training participation.
openaire +4 more sources
Britain’s Older Employees in Decline, 1990-2006: a panel analysis of pay
, 2017 Older employees’ wages and earnings declined over the period 1991–2006, when compared with younger employees. The overall fall in relative wages was about 18 per cent, and for relative earnings 21 per cent.
Deborah Smeaton +3 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
International Journal of Occupational Medicine and Environmental HealthObjectives Stereotype threat arises when an individual worries about the possibility of confirming or being perceived through the lens of a negative stereotype about one’s group.
Zofia Mockałło +2 more
doaj +1 more source
Primenjena Psihologija, 2016 In our study we explored generational differences in psychological contract content (PCC) and reactions to psychological contract breach (PCB) among Croatian employees.
Mojra Dautović, Zvonimir Galić
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Economic fluctuations and retirement of older employees [PDF]
This paper studies the way in which labor market fluctuations affect the transition to early retirement among older employees in Sweden via the practice of negotiated pensions.
Hallberg, Daniel
core