Results 71 to 80 of about 665 (160)

Prophylactic and Therapeutic Inhibition of In Vitro SARS-CoV-2 Replication by Oleandrin [PDF]

, 2020
ABSTRACT With continued expansion of the COVID-19 pandemic, antiviral drugs are desperately needed to treat patients at high risk of life-threatening disease and even to limit spread if administered early during infection. Typically, the fastest route to identifying and licensing a safe and effective antiviral drug is
Kenneth S. Plante, Jessica A. Plante, Diana Fernandez, Divya Mirchandani, Nathen Bopp, Patricia V. Aguilar, K. Jagannadha Sastry, Robert A. Newman, Scott C. Weaver   +8 more
openaire   +2 more sources

Retraction: Oleandrin: A cardiac glycosides with potent cytotoxicity

Pharmacognosy Reviews, 2016
[This retracts the article on p. 131 in vol. 7, PMID: 24347921.].
openaire   +3 more sources

Network pharmacology-based toxicity, molecular docking, and molecular dynamics analysis of phytoconstituents from roots of Nerium indicum L

Pharmacological Research - Modern Chinese Medicine
Background: Herbal medicine plays a vital role in healthcare, but safety concerns arise due to potential toxicity risks. Nerium indicum (夹竹桃, jiā zhú táo) is used in Chinese herbal medicine for its therapeutic effects, yet it contains toxic cardiac ...
Veerkumar P. Japti, Mrityunjaya B. Patil, Banappa S. Unger, Shamanand P. Mallapur, Akshay Shamnewadi, Vishal S. Patil, Sathgowda Patil, Anand V. Desai   +7 more
doaj   +1 more source

Erratum: The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, is Synergistic With Radiotherapy in Models of Human Glioblastoma

Frontiers in Pharmacology, 2022
Frontiers Production Office
doaj   +1 more source

EFFECT OF ACTIVE MOLLUSCICIDAL COMPONENETS OF ABRUS PRECATORIUS, ARGEMONE MEXICANA AND NERIUM INDICUM ON CERTAIN ENZYMES IN THE NERVOUS TISSUE OF LYMNAEA ACUMINATA [PDF]

Journal of Sciences, Islamic Republic of Iran, 2000
In vivo and in vitro sublethal exposure of abrin, glycyrrhizin (active component of Abrus precatorius seed and root), sanguinarine, protopine (Argemone mexicana seed) and oleandrin (Nerium indicum leaf) inhibited the acetylcholinesterase, lactic ...
doaj  

Preliminary investigation of the safe dose of oleandrin when administered orally to Beagles

Journal of the American Veterinary Medical Association
Abstract OBJECTIVE The purpose of the study reported herein was to determine the dose of oleander extract and oleandrin (the key pharmacologically active constituent) that could be safely administered PO to dogs. ANIMALS 42 purebred Beagle dogs were used to study an extract of Nerium oleander.
Theresa W, Fossum, Robert A, Newman, Jose R, Matos   +2 more
openaire   +2 more sources

Oleandrin [PDF]

, 2020
openaire   +1 more source

Small molecule regulators of microRNAs identified by high-throughput screen coupled with high-throughput sequencing. [PDF]

Nat Commun, 2023
Nguyen LD, Wei Z, Silva MC, Barberán-Soler S, Zhang J, Rabinovsky R, Muratore CR, Stricker JMS, Hortman C, Young-Pearse TL, Haggarty SJ, Krichevsky AM.   +11 more
europepmc   +1 more source

Yellow oleander (Thevetia peruviana) toxicosis in 4 goats. [PDF]

J Vet Diagn Invest, 2023
Sykes CA, Filigenzi M, Uzal FA, Poppenga RH.   +3 more
europepmc   +1 more source

Water-soluble egg membrane enhances the immunoactivating properties of an Aloe vera-based extract of Nerium oleander leaves

Clinical, Cosmetic and Investigational Dermatology, 2016
Kathleen F Benson,1 Robert A Newman,2,3 Gitte S Jensen1 1NIS Labs, Klamath Falls, OR, 2Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, 3Nerium Biotechnology Inc, San Antonio, TX, USA Objective: To evaluate
Benson KF, Newman RA, Jensen GS
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